Biochemistry

Breaking the biofilm barrier: CRISPRi-guided investigation of Pseudomonas aeruginosa susceptibility to natural products

Wu, Sherrie (2025)

Antibiotic resistance is a growing concern, with pathogens such as Pseudomonas aeruginosa evolving resistance to clinical treatments. Furthermore, our race against antibiotic resistance is worsened by a slowdown in novel ...
INVESTIGATING THE ROLE OF CYTOKINES AND REGULATORY T CELLS IN A NOVEL TREATMENT FOR GRAFT-VERSUS-HOST DISEASE USING EXOSOMES FROM ACTIVATED MESENCHYMAL STROMAL CELLS

Martell, Ella (2025)

The development of graft-vs-host disease (GVHD) is a significant complication in the treatment of leukemia, wherein the graft of transplanted hematopoietic tissues from a donor (allo-HCT) attacks the recipient cells of the ...
RecA and Topoisomerase III in Post Replication Gap Repair

Dunbar, Emma (2025)

Post replication gaps occur when a DNA polymerase skips a section of damaged DNA during replication. These gaps of single stranded DNA must be repaired for the cell to survive. In E. coli the repair pathway proceeds with ...