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Evaluation of nutrient concentrations and genetic presence of cyanobacteria and their cyanotoxins in Lake Onalaska
(2024-08)
Aquatic cyanobacteria blooms are becoming a global environmental concern due to their
ability to produce secondary metabolites in the form of toxins. It is important to
determine the abundance of genes specific to ...
Impact of exercise-induced extracellular vesicles on RAW 264.7 macrophage gene expression
(2024-01)
The overall process and outcome of muscle regeneration is well established yet communication nuances between different body systems during this process aren’t fully elucidated. One potential communication molecule is the ...
Fructose dehydrogenase characterization in the pursuit of creating a fructose biosensor
(2023-12)
Nonalcoholic fatty liver disease (NAFLD) is a major health issue that can lead to cirrhosis and even death. One marker of NAFLD is increased fructose in the blood and other tissues, which is possible to measure with a ...
Development of a serum-antibody test specific for a bacterium associated with rheumatoid arthritis patients
(2021-08)
Rheumatoid arthritis (RA) is an incurable inflammatory autoimmune disease of synovial
joints that affects nearly 1% of the global population and an estimated 1.36 million
Americans. The disease has significant economic ...
Development of antiviral edible films against Tulane virus, a human norovirus surrogate, for use on strawberries
(2022-05)
This study developed and evaluated the antiviral properties of edible films against Tulane virus, a human norovirus surrogate. The antiviral properties of carvacrol, grape seed extract (GSE), and green tea extract (GTE) ...
The bactericidal mechanism of action of the SK-03-92 antibiotic against Staphylococcus aureus and the eradication of SK-03-92-induced bacterial persistence
(2019-12)
Infections caused by Staphylococcus aureus kill approximately 52 Americans every day and are particularly lethal when a biofilm has formed. The development of persister cells, and thus a chronic infection, further increases ...
Generation of monoclonal antibodies to ferret immune cell proteins in support of the ferret model to study human influenza infection
(2019-08)
Influenza is a highly contagious viral pathogen that causes respiratory illness in humans and animals. It is a major public health threat, resulting in three to five million yearly illnesses and up to 300,000 deaths ...
ESCRT pathway involvement in the release of human parainfluenza virus virions and matrix protein
(2019-08)
It has been shown that some enveloped viruses utilize cellular components to help facilitate viral budding and release. With these viruses, a viral protein interacts with the cellular ESCRT machinery, which is involved in ...
Development of intestinal dysbiosis and necrotizing enterocolitis in infants and the treatment of enterocolitis
(2019-12)
The human gut microbiota is a complex ecosystem of trillions of microorganisms that provide health benefits to the host. Gut colonization begins at birth and is affected by five primary factors – mode of delivery, antibiotic ...
Characterization of HPIV3 matrix mutants deficient in budding
(2019-12)
The matrix (M) protein of human parainfluenza virus type 3 (HPIV3) is important for directing assembly and release of new virus; however, the mechanism of release remains unclear. Identifying domains of M required for ...