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Induced Chiral Mesophases from Achiral Naphthoate Derivatives in Self-Assembled Systems
(2022-04)
The enhanced ordering arrangement of liquid crystals has been documented for well over a century, but the increase in popularity of inducible mesophases has emerged as a leading optioelectronic material. Applications ...
Recovery of Gold Nanoparticle Waste
(2022-04)
The purpose of this project is to determine an effective method for recovering gold from nanoparticle waste. Nanoparticle research is a significant field of research; however, the use of nanoparticles in this research often ...
Application of Spectroscopic Techniques to Study Molecular Crowding Effects on the Structure and Functions of Escherichia coli Prolyl-tRNA Synthetase
(2022-04)
Many in vitro experiments with enzymes are performed in dilute conditions that do not resemble the cellular environment, which is crowded with various biomolecules. Crowding can impact an enzyme's structure, intrinsic ...
Studying the Electrochemical Activity of Methanol Dehydrogenase in Lanthanide-Modified Methylobacterium Extorquens
(2024-04)
Recent studies have demonstrated that some enzymes in bacteria isolated from lanthanide-rich areas use lanthanides as metal cofactors in place of more common metals like calcium and that these lanthanide-enzymes have ...
Probing the Effects of Molecular Crowding on Protein Structure Using Atomic Force Microscopy
(2024-04)
Enzymes exist in crowded cellular environments. However, conventionalin vitroandin silicoenzymatic studies are conducted in dilute conditions that do not consider the molecular crowding effects on an enzyme's structure and ...
Computational Analysis of the Structural and Energetic Properties of the Sulfamic Acid Zwitterion
(2024-04)
The zwitterion of sulfamic acid, formed from ammonia (NH3) and sulfur trioxide (SO3), has been identified as a possible intermediate in the formation of atmospheric aerosol particles. We are interested in the degree to ...
Three-State Biaryl Lactone Molecular Switches with Amine Donors
(2022-04)
Our research is focused on the synthesis of four bridged biphenyl molecules with amine donors. These three-state biphenyl molecules, due to their chemical properties, should have various uses within chemical and electronic ...
Probing the Binding Between the Receptor-Binding Domain of the α-, β-, and OVariants of SARS-CoV-2 and the Human Angiotensin-Converting Enzyme 2 Receptor Using Computer-aided Simulations
(2022-04)
The structure of severe acute respiratory syndrome coronavirus 2 (SARSCoV-2) is characterized by its distinct spike proteins housing the receptor-binding domain (RBD). The RBD binds directly to the human extracellular ...
Investigating the Effects of Molecular Crowding on Substrate- Binding using Isothermal Titration Calorimetry and STD-NMR
(2024-04)
Conventional in vitro methods use buffers and salts to mimic the intracellular environment. However, by simplifying the in vivo environment, these methods lack essential structural elements that have been shown to impact ...
Use of Raman Spectroscopy as a Noninvasive Tool for Cancer Detection in Human Saliva
(2024-04)
Cancer now tops heart disease as the number one cause of death in the United States and is the second leading cause of death globally, accounting for an estimated 9.6 million deaths in 2018. There is an urgent need for ...