| dc.description.abstract | Whole genome duplication (WGD) is an important evolutionary mechanism that can
facilitate adaptation and speciation. The salmonid family represents an ideal model to
study the effect of WGDs because of the extensive diversity that has evolved following
WGD by autotetraploidization in the common ancestor. As salmonids evolved and
diversified after the WGD, much of the genome returned to a diploid state. However,
~20% of the genome display residual tetrasomy, and the genomic processes that
influence rediploization are still poorly understood. To refine the understanding of the
effects of the WGD in salmonids, female (20,450 loci) and male (6,340 loci) linkage
maps were constructed for cisco Coregonus artedi. These linkage maps identified
homologous chromosomes for three coregonines and one representative species for each
of Salmo, Salvelinus, and Oncorhynchus genera and the nonduplicated sister group of
salmonids, Esox. Using this information, a cross species comparison of homeologous
regions was conducted to identify regions that still exhibit residual tetrasomy, that
diverged prior to speciation, and intermediate regions that are diverging independently.
The further development of genomic resources in less described salmonids will aid in
understanding genomic variation post-WGD. Additionally, the linkage map constructed
here will facilitate future research with the aim of determining the degree of heritable
genetic differences among cisco forms. | en_US |
