Long term effects of pre-workout supplementation on clinical health markers in recreationally active females

Abstract

Consuming a multi-ingredient pre-workout supplement (MIPS) to enhance physical capabilities has become increasingly popular. However limited data is available regarding the long term safety of consuming such products. Therefore, the purpose of this study was to examine the effects of pre-workout supplementation on health measurements in recreationally active females. Subjects reported to the laboratory for baseline and identical post-data measurements which included blood pressure, heart rate, and blood lipids. They were then randomly assigned to ingest one serving of the pre-workout supplement or placebo daily during a 7-week period. All subjects also completed a standardized strength training program 3 times per week and were provided dietary recommendations. No significant group x time interactions were observed for heart rate (p=0.43), systolic blood pressure (p=0.18), diastolic blood pressure (p=0.20), high density lipoproteins (p=0.92), low density lipoproteins (p=0.93), triglycerides (p=0.96), or total cholesterol (p=0.99). There was a significant main effect for time observed for diastolic blood pressure which decreased over the course of the study (p ≤ 0.001). Ingesting a MIPS for 7 weeks does not appear to negatively influence clinical markers of health in active females.