Browsing Biochemistry Honors Theses and Research Papers by Issue Date
Now showing items 1-20 of 84
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The effect of neuropeptides on growth and function of bovine articular chondrocytes
(2007)Cartilage injury is a central issue in orthopedics to which there is no known physiological treatment. Neuropeptides playa role in the proliferative and reparative processes of many tissue types, but little is known about ... -
Stable expression and purification of Juvenile Hormone Binding Protein from Drosophila melanogaster Schneider line-2 cells
(2007)Studies on the hemolymph Juvenile Hormone Binding Protein (hJHBP) and Juvenile Hormone (JH) interaction have been considerably limited by the availability of pure hJHBP. An expression vector was created by cloning the ... -
Identification of two binding partners for the bacterial actin homolog MreB
(2007)A distinguishing characteristic of prokaryotes was long thought to be the lack of a cytoskeleton similar to eukaryotes consisting of actin filaments, microtubules, and intermediate filaments. However, recent work has shown ... -
Identification of the Functional Domains of Arabidopsis FLS2
(2007)Arabidopsis FLS2 is a leucine-rich repeat (LRR) transmernbrane receptor-kinase that recognizes bacterial flagellin and induces plant innate immune responses. Flg22 is a 22 amino acid peptide based on a sequence of flagellin ... -
Isolation and characterization of Drosophila melanogaster central processing mutants
(2007)The aim of this study is to isolate and characterize mutant fruit flies (Drosophila melanogaster) which are defective in central processing, with the ultimate goals of! finding the genes necessary for this process to ... -
Engineering of maltose-binding protein to employ a poly-arginine tag and improve protein purification
(2007)Maltose binding protein (MBP), a solubility-enhancing fusion protein, has demonstrated great success in the application of protein purification when fused to a protein of interest. It has already been engineered to include ... -
Optimization of recombinant E. coli protein expression in growth medium
(2007)With the onset of novel genomic sequence data, much effort is now being taken to discover the role of many genes and the corresponding proteins that remain unknown. One of the limiting steps in such efforts has been the ... -
Characterization of ZIIR element of BZLF1 promoter in the context of the whole Epstein - Barr Virus genome
(2007)Latent infection of Epstein-Barr virus (EBV) is associated with many human cancers. Induction of lytic replication of EBV may lead to destruction of these tumor cells. The viral immediate-early gene, BZLF1, plays a key ... -
MHC class I allele characterization in Indonesian cynomolgus macaques
(2007)There has recently been increased interest in the use of cynomolgus macaques for the study of infectious diseases. However, little focus has been given to studying the immunogenetics of these animals. To improve researcher’s ... -
Tanscriptome comparison of ionizing radiation resistant strain of Escherichia coli, CB2000, and naturally occurring strain of Escherichia coli, Founder
(2007)CB2000 is a strain of Escherichia coli (E. coli) that is extremely resistant to ionizing radiation. It was derived from a colony, referred to as the founder strain, isolated from naturally occurring Escherichia coli K12 ... -
A genetic approach to understanding co-regulated MAPK genes in Arabidopsis thaliana
(2007)Mitogen-activated protein kinase (MAPK) signaling cascades connect cellular signal and gene transcription in cells. The pathway can regulate cell division, cell growth, and other pathways in eukaryotes. We used the ... -
The Effects of Doa4 and Other Multivesicular-Body Proteins on Brome Mosaic Virus Replication in Yeast
(2008)Brome Mosaic Virus (BMV) replication was measured in yeast single and double deletion mutants of Doa4 and other proteins in the multivesicular-body (MVB) pathway in order to determine the role of Doa4 and other MVB proteins ... -
Cleavage and Polyadenylation Specific Factor 6 (CPSF6): A possible protein mediator for CARM1 and pre-MRNA splicing
(2008)Coactivated associated methyltransferase 1 (CARM1), an enzyme that regulates cellular processes via arginine methylation, has been suggested to play a role in RNA processing and alternative splicing. The focus of this ... -
Defining the PIPKIgamma707/SNX5 interaction and its possible association with E-cadherin
(2008)E-cadherin, a cell adhesion molecule and tumor suppressor plays an important role in suppressing metastasis of cancers of epithelial origin by acting as the cornerstone of adherens junctions, which facilitate adhesion ... -
Inflammatory response and extracellular matrix turnover following pulsed dyed laser treatment of vocal fold and vocal fold fibroblasts
(2008)The 585-nm pulsed dye laser (PDL) is commonly utilized for the treatment of vascular and epithelial vocal fold lesions; however there are anecdotal reports that it may improve scar outcomes, perhaps by altering extracellular ... -
Inhibition of the Escherichia coli replication cycle by a mutant RecA protein
(2008)Abstract: A conserved [K/R]x[K/R] motif is found at the subunit-subunit interface in bacterial RecA protein filaments. In the Escherichia coli RecA protein, this motif is made up of residues K248 and K250. Both of these ... -
The effects of erythropoietin on transferrin receptor concentration in rat duodenum tissue
(2008)Preliminary studies showed factors contained in human milk retain their mitogenic activity following pasteurization. Iron is critical in cell proliferation in early life. Erythropoietin (Epo), a factor found in human milk, ... -
Chronic and acute seizure activity affects NKCC1 and KCC2 expression and alters GABA-induced inhibition in the adult and developing hippocampus
(2008)Temporal lobe epilepsy is a relatively common nervous system disorder characterized by abnormal activity in the hippocampus, often caused by a decrease in GABA inhibition. GABAA receptors are Cl- ion channels whose effects ... -
Characterization of Tau Phosphorylation During the Differentiation of Human Embryonic Stem Cells
(2008)Alzheimer's disease is the seventh leading cause of death in the United States with an estimated cost of 100 billion dollars. The severity of this neurodegenerative disease is strongly correlated with the number of ...