Browsing Student Research Day by Author "Bailey-Hartsel, Scott"
Please Don't Fade Away : Rebooting a Robust Series of Organelle-Specific Fluourescence Probes for New Purposes Smith, Danielle; Ross, Rachel; Win, Nay Myo (2015-04)Our ultimate goal is to develop and license or market a specific set of probes which can be used to quantitatively and qualitatively monitor organelles, membrane domains, pH gradients and membrane potentials in live cells.
Spectroscopic Studies to Explore the Impact of Macromolecular Crowding on the Structure and Function of Escherichia coli of Prolyl-tRNA Synthetase Adams, Lauren; Andrews, Ryan; Schmit, Heidi; Bailey-Hartsel, Scott; Hati, Sanchita (2016-10-14)Most computational and experimental studies to understand the molecular mechanism of an enzyme-catalyzed reaction are usually performed in dilute solutions. However, enzymatic activities in vivo occur in a crowded environment ...
Ross, Rachel; Tourville, Claudia; Rigden, Gabrielle; Lewis, David E.; Bailey-Hartsel, Scott (2017-04-07)The purpose of this study was to show that the poorly-tolerated antifungal drug Amphotericin B (AmB) causes collateral damage in human cells in part by depolarizing (short-circuiting) mitochondria, the powerhouses of the cell.