Chris Coe talks about his family and background, his early education, the City College of New York, and his graduate studies at Downstate Medical Center and Stanford Medical School. He talks about his research on the immune system, his recruitment to UW Primate Laboratory, teaching, and his students. He discusses the Department of psychology, his directorship of Harlow Primate Lab, the utility of his research, his work on the concept of stress, and on the biology of aging. He talks about the animal rights movement and how it affected his research. He talks about his research on HIV and flu, and a student's work on post-traumatic stress disorder. He discusses the culture of the department, the physical facilities, and his graduate student instruction. He talks about his time on the Animal Care and Use Committee and trends in the animal rights movement. He talks about his involvement with the Health Emotions Research Institute and other research centers and programs. He talks about the changes in UW administration, the relationship of UW with state legislature and the population, the UW student body. He ends by discussing significant concerns about the UW administration and the future of the Harlow lab.