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Evaluating the effects of a possible therapeutic drug for Rett Syndrome in a mouse model
(2010)
Rett Syndrome (RTT) is a neurodevelopmental disorder that affects girls with an estimated prevalence of 1 in 10,000-15,000, with no current cure or effective treatment. Most RTT cases are caused by human methyl-CpG binding ...
A role for FoxQ-1 in memory and learning
(2010)
Using a genome-wide screen, genes that were differentially expressed between aged rats that were able to learn a spatial task (aged superior learners: SL), and learning-impaired rates (AI) were identified in the CA1 region ...
Transmission ratio distortion in the hybrid offspring of three mouse subspecies
(2010)
A crucial component of understanding the origin or new species is understanding how reproductive isolation evolves between divergent populations. The relative importance of Dobzhansky-Muller incompatibilities as compared ...