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Reduction of androgen induced reactive oxygen species (ROS) production as a method of preventing prostate cancer
(2007)
Prostate cancer is a leading cause of cancer deaths among men and development of a preventative agent is urgently needed. Reactive oxygen species (ROS) are carcinogens and are linked to prostate tumor development. ROS ...
The Biochemical Characterization of a Translational Repressor
(2008)
Iron regulatory proteins (IRP) are crucial post-transcriptional regulators of iron metabolism. They influence the synthesis of proteins involved in iron uptake, storage and use by binding to their mRNAs. IRP1 stands out ...
Activation and suppression of macrophages: implications for cancer immunotherapy
(2006)
It is widely known that macrophages can be activated to kill tumor cells. It is also known that tumor-infiltrating macrophages can be immunosuppressed. The mechanisms of both tumor killing by activated macrophages and ...