Search
Now showing items 1-6 of 6
Investigating the Role of SDHB in Cardiac Regeneration
(2023)
Heart failure is the leading cause of death in the United States. The long wait for heart
transplants and the risk of graft rejection has motivated heart regeneration research to advance
heart failure treatment. Importantly, ...
Investigation of the role of CarD in transcription initiation and the stringent response in Zymomonas mobilis
(2023)
In some prokaryotes, transcriptional regulator CarD stabilizes the open promoter complex
during transcription initiation. As both a transcriptional activator and repressor, CarD can be
used to coordinate gene expression ...
α7-Nicotinic Acetylcholine Receptor Signaling in Cardiac Regeneration
(2020-05)
Heart disease is the leading cause of death in the U.S. Loss of heart regenerative capacity in adult mammals is a principle reason why adults fail to recover from heart diseases. In contrast, neonatal mammals possess ...
Single Nuclei RNA Sequencing of Mice Hippocampus to Evaluate in vivo Gene Editing by a Biodegradable Nanocage for CRISPR/Cas9 Ribonucleoproteins
(2021)
In recent years, CRISPR-Cas9 technology has shown promise as a versatile gene editing
tool that enables precise nucleotide base-editing (Sander & Joung, 2014), and are anticipated to
drive the next wave of gene therapies ...
Genes, Neonatal Nursery and Biobehavioral Development
(2022)
Evidence suggests that early life stress (ELS) has significant impacts on development and health. Neonatal intensive care unit (NICU) placement may be a form of ELS. Better understanding of the consequences and risk factors ...