Browsing Genetics Honors Theses and Research Papers by Title
Now showing items 9-28 of 37
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Genes, Neonatal Nursery and Biobehavioral Development
(2022)Evidence suggests that early life stress (ELS) has significant impacts on development and health. Neonatal intensive care unit (NICU) placement may be a form of ELS. Better understanding of the consequences and risk factors ... -
A genetic approach to understanding co-regulated MAPK genes in Arabidopsis thaliana
(2007)Mitogen-activated protein kinase (MAPK) signaling cascades connect cellular signal and gene transcription in cells. The pathway can regulate cell division, cell growth, and other pathways in eukaryotes. We used the ... -
Going from embryo to adult: How zebrafish zic genes are regulated during development
(2009)This project aims to further our understanding of developmental genetics by identifying unknown transcription factor binding sites that play an important role in regulating zic2a, a gene required for proper neural development ... -
Haplotype frequencies at the miR156 and miR172 transcript regions show a significant response to divergent recurrent selection for vegetative phase change in maize
(2009)Sweet corn (Zea mays L). plants that transition from juvenility to the adult phase earlier during development are generally more resistant to common rust (Puccinia sorghi), a disease that causes substantial yield loss in ... -
The Identification and Characterization of Cytoplasmic Acetylated Lysines
(2011)Lysine acetylation by histone acetyl transferascs (HATs) is a reversible posttranscriptional modification that plays a key role in regulating several biological processes, such as the cell cycle, nuclear transport, and ... -
Identification Of Acetylated Lysine Residues On The ER Chaperone BiP
(2011)Alzheimer's disease (AD) pathogenesis involves the abnormal production of a small peptide called Abeta. The rate-limiting enzyme for the generation of Abeta is BACEl and, as such, its downregulation decreases Abeta levels. ... -
Identification of QTLs for voluntary running activity in mice for the CBA/J and DBA/2J mouse strains
(2009)Our goal is to understand the genetic factors related to voluntary running activity. Voluntary running activity in humans and mice is known to be a heritable behavioral trait. The genetic factors influencing voluntary ... -
Investigating the Role of SDHB in Cardiac Regeneration
(2023)Heart failure is the leading cause of death in the United States. The long wait for heart transplants and the risk of graft rejection has motivated heart regeneration research to advance heart failure treatment. Importantly, ... -
Investigation of the role of CarD in transcription initiation and the stringent response in Zymomonas mobilis
(2023)In some prokaryotes, transcriptional regulator CarD stabilizes the open promoter complex during transcription initiation. As both a transcriptional activator and repressor, CarD can be used to coordinate gene expression ... -
An investigation on the effects of mutations in the ATG12 autophagy pathway of Arabidopsis thaliana
(2007)Under nutrient-deficient conditions, plants are forced to recycle secondary cellular constituents to conserve energy for the more essential processes (Klionsky, et al. 2000). Plants accomplish this through a process called ... -
Measuring mitochondrial nonenyzmatic lysine acetylation
(2017-05-15)Protein acetylation is a regulatory modification affecting numerous biochemical and cellular processes. Over half of the proteins in mitochondria have been identified as acetylated, however mechanism of acetylation has not ... -
Nurr1 knockout in substantia nigra proposed to result in cognitive deficits in Rattus norvegicus
(2017-06-13)Many Parkinson's disease (PD) patients suffer from cognitive impairment. Reduced secretion of dopamine (DA) from substantia nigra (SN) to striatum results in motor deficits in PD patients, but little is known about its ... -
Pilot screen for second site suppressors of wstd
(2009)Triosephosphate isomerase (TPI) loss of function (wstd), in flies has been shown to have increases in methylglyoxal and advanced glycation end products (AGEs) which have also been found in increased levels in diseases ... -
The potential functional consequences of mandible shape evolution in giant house mice from Gough Island
(2017-06-13)An extremely large-bodied Mus musculus domesticus mouse population from the remote Gough Island (GI) were used to study how the evolution of shape may affect the performance of a morphological trait. The study question ... -
Preneoplastic Lesion Growth in B6.Hcs7C3H 219R8 Congenic Hepatocarcinogen-Sensitive Mus musculus
(2009)A region of mouse Chromosome 1, called the Hcs7 locus, is involved in the susceptibility to liver carcinogenesis in the inbred mouse strain, C3H/HeJ (C3H). Linkage analysis of a cross between C3H and a strain that is ... -
The PrkA phosphosubstrate GpsB in Listeria monocytogenes promotes cell wall stress responses
(2021)None provided -
Quantification of interneurons present in postmortem adult Down syndrome Brain
(2017-06-13)Neuroanatomical abnormalities in the DS brain contribute to specific cognitive deficits in DS individuals. Histopathology has consistently revealed fewer neurons in the DS cerebral cortex. Based on neuron morphology and ... -
Reduction of androgen induced reactive oxygen species (ROS) production as a method of preventing prostate cancer
(2007)Prostate cancer is a leading cause of cancer deaths among men and development of a preventative agent is urgently needed. Reactive oxygen species (ROS) are carcinogens and are linked to prostate tumor development. ROS ... -
A role for FoxQ-1 in memory and learning
(2010)Using a genome-wide screen, genes that were differentially expressed between aged rats that were able to learn a spatial task (aged superior learners: SL), and learning-impaired rates (AI) were identified in the CA1 region ... -
The role of a soluble, competitive FGF receptor in embryonic stem cell-derived hematopoiesis
(2007)The fibroblast growth factor (FGF) signaling pathway plays a pivotal role in the maintenance of embryonic stem cells (ESCs) as well as their differentiation into the hematopoietic lineage. We observed that supplementing ...