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LEF/TCF family transcription factors are important in the upregulation and restricted expression of zic genes in the dorsal neural tube
A central question in biology is how different cell-types arise from an initially one-celled embryo to form an organism. Many cellular differences arise through differential gene expression in space and time via the action ...
Going from embryo to adult: How zebrafish zic genes are regulated during development
This project aims to further our understanding of developmental genetics by identifying unknown transcription factor binding sites that play an important role in regulating zic2a, a gene required for proper neural development ...
The role of offspring in mitigating extreme stress in lactating female mice
Mothers of many species find great comfort in their offspring, which in turn has been found to alleviate mild stress in the mother. In the face of a life-threatening event, however, do offspring still act as effective ...