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A role for FoxQ-1 in memory and learning
(2010)
Using a genome-wide screen, genes that were differentially expressed between aged rats that were able to learn a spatial task (aged superior learners: SL), and learning-impaired rates (AI) were identified in the CA1 region ...
In vitro screenings predict polymer ability to facilitate RNAi through its use as a delivery vehicle of siRNA
(2009)
Gene therapy techniques have emerged in recent decades as a method of combating genetic disorders. One prospective branch of gene therapy is using RNA Interference (RNAi) to regulate gene expression. RNAi employs small ...
Genetic studies of the velC gene required for proper sexual development in Aspergillus nidulans
(2010)
VelC is required for the proper fungal development in Aspergillus nidulans.
Velvet proteins, VeA, VosA, VelB, and VelC, are a new protein family in many filamentous fungi. They regulate fungal development and secondary ...
Regions of functional upstream domain of protein F1 of streptococcus pyogenes necessary for exposure of tenth type III module in fibronectin
(2010)
The 49 amino acid portion of the F1 surface protein of Streptococcus pyogenes known as the functional upstream domain (FUD) interacts with Fn in an unknown manner that prevents assembly of a Fn matrix. When FUD binds to ...
Steam distilled extract of ginger is a potent mediator of apoptosis in endometrial cancer cells via the modulation of the p53 and BcI-2 pathways
(2012)
Development for new therapeutic and preventative agents in the treatment of gynecological cancers is in constant need. In the cunent study, we demonstrate that the steam distilled extracts of ginger are potent mediators ...
Characterization of ZIIR element of BZLF1 promoter in the context of the whole Epstein - Barr Virus genome
(2007)
Latent infection of Epstein-Barr virus (EBV) is associated with many human cancers. Induction of lytic replication of EBV may lead to destruction of these tumor cells. The viral immediate-early gene, BZLF1, plays a key ...
MHC class I allele characterization in Indonesian cynomolgus macaques
(2007)
There has recently been increased interest in the use of cynomolgus macaques for the study of infectious diseases. However, little focus has been given to studying the immunogenetics of these animals. To improve researcher’s ...
Tanscriptome comparison of ionizing radiation resistant strain of Escherichia coli, CB2000, and naturally occurring strain of Escherichia coli, Founder
(2007)
CB2000 is a strain of Escherichia coli (E. coli) that is extremely resistant to ionizing radiation. It was derived from a colony, referred to as the founder strain, isolated from naturally occurring Escherichia coli K12 ...
A genetic approach to understanding co-regulated MAPK genes in Arabidopsis thaliana
(2007)
Mitogen-activated protein kinase (MAPK) signaling cascades connect cellular signal and gene transcription in cells. The pathway can regulate cell division, cell growth, and other pathways in eukaryotes. We used the ...
Mid-life dementia risk scores as a predictor of CSF biomarker and cognitive response to simvastatin therapy in asymptomatic adults at risk for Alzheimer's disease: The ESPRIT trial
(2010)
BACKGROOUND: Cardiovascular risk factors at mid-life are associated with an increased risk of developing Alzheimer's disease (AD).
OBJECTIVE: Determine relationships between baseline dementia risk, cognitive function, CSF ...