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Now showing items 21-30 of 31
Lithium and its effects on a novel (non drug-induced) hyperactive mouse model
(2010)
Bipolar disorder (BPD) is a devastating long-term disease for which a significant symptom is mania. Researchers have long relied on the use of rodent models to study psychological disorders (like BPD), as well as to develop ...
Identifying and locating length and position of introgression on chromosome 6 influencing resistance to bacterial wilt and identifying markers for bacterial wilt resistance on chromosome 12
(2010)
Bacterial wilt is a devastating disease affecting hundreds of species of plants and millions of people by destroying crops like the tomato. Conventional techniques to destroy the pathogen have been futile to this point and ...
TRPV1 mediates matrix metalloproteinase expression in spinal cord injury-induced chronic neuropathic pain
(2009)
Neuropathic pain (NP) is common following spinal cord injury (SCI). Evidence exists for the involvement of many processes in NP development following SCI (Cain et al, 2007). Our past studies identified increased expression ...
Attempts to analyze the RNA-binding specificity of the C. elegans RNP-8 protein
(2010)
Cytoplasmic polyadenylation is a key mechanism of gene regulation in all eukaryotes. The C. elegans GLD-2 protein provides the catalytic activity for a cytoplasmic poly(A) polymerase, but GLD-2 must partner with another ...
Steam distilled extract of ginger is a potent mediator of apoptosis in endometrial cancer cells via the modulation of the p53 and BcI-2 pathways
(2012)
Development for new therapeutic and preventative agents in the treatment of gynecological cancers is in constant need. In the cunent study, we demonstrate that the steam distilled extracts of ginger are potent mediators ...
Studies on the heat stability of egg yolk antibody (lgY)
(2007)
Nutritionally and economically-important heat-labile proteins, including enzymes, hormones, and antibodies (Ab), lose a substantial amount of activity following industrial processing. Protection of these heat-sensitive ...
Utilizing oscillating magnetic fields to manipulate embryonic tissues
(2007)
Embryonic mouse tissues were incubated with gold-coated iron conjugated to a p75 antibody and then exposed to an oscillating magnetic field (OM). The p75 antibodies tag neural crest-derived cells, and via this interaction ...
Gaze-evoked blinks in rhesus monkeys
(2007)
Gaze-evoked blinks, blinks that occur during rapid movements of the head and eyes, are believed to be the result of a shared mechanism that is responsible for a blink occurring with a saccade. In humans, it has been found ...
LEF/TCF family transcription factors are important in the upregulation and restricted expression of zic genes in the dorsal neural tube
(2009)
A central question in biology is how different cell-types arise from an initially one-celled embryo to form an organism. Many cellular differences arise through differential gene expression in space and time via the action ...
Activation and suppression of macrophages: implications for cancer immunotherapy
(2006)
It is widely known that macrophages can be activated to kill tumor cells. It is also known that tumor-infiltrating macrophages can be immunosuppressed. The mechanisms of both tumor killing by activated macrophages and ...