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Now showing items 11-20 of 31
ANTITUMOR EFFECTS OF ANTl-CD40/CPG IMMUNOTHERAPY COMBINED WITH GEMCIT ABINE OR 5-FLUOROURACIL CHEMOTHERAPY IN THE B 16 MELANOMA MODEL
(2013)
Our previous studies demonstrated that anti-CD40 mAb (anti-CD40) can synergize with CpG oligodeoxynucleotides (CpG) to mediate antitumor effects by activating myeloid cells such as macro phages in tumor-bearing mice. ...
Neuronal lysosome permeabilization dynamics in ischemia
(2009)
The mechanism in which lysosomes are damaged by free radicals during neuronal ischemia is examined in rat hippocampus. There are two hypotheses. The free radicals can degrade the lysosome membrane through liquefaction; all ...
Reduction of androgen induced reactive oxygen species (ROS) production as a method of preventing prostate cancer
(2007)
Prostate cancer is a leading cause of cancer deaths among men and development of a preventative agent is urgently needed. Reactive oxygen species (ROS) are carcinogens and are linked to prostate tumor development. ROS ...
The Biochemical Characterization of a Translational Repressor
(2008)
Iron regulatory proteins (IRP) are crucial post-transcriptional regulators of iron metabolism. They influence the synthesis of proteins involved in iron uptake, storage and use by binding to their mRNAs. IRP1 stands out ...
Delta-opioid receptor (DOR) activation prolongs respiratory motor output during oxygen-glucose deprivation (OGD) in neonatal rat spinal cord in vitro
(2007)
Severe reduction of blood flow to the brain results in oxygen-glucose deprivation (OGD) and neuronal damage. DOR activation is neuroprotective during OGD in the cerebellum and cortex, but it is not known whether DOR ...
The effects of inter-personal factors on bird and bat mortality searcher efficiency
(2010)
Employee efficiency and performance are essential to the success of a project. These inter-personal factors have been investigated in specific settings but have not been explored in the scientific research assistants. This ...
Bacterial Community Spatial and Temporal Variation in a North Temperate Bog Lake
(2012)
Bog lakes such as Mary Lake in northern Wisconsin are ideal systems to investigate microbial communities due to easily identified spatial boundaries and well characterized seasonal ecosystem dynamics. Multiple factors are ...
Present management practices and future possibilities for the Concha Prieta (Anadara tuberculosa) in the community of San Felipe, Ecuador
(2007)
San Felipe is a small fishing village on the Caraquez estuary on the coast of Ecuador. Only twenty years ago, this community was able to sustain itself on clam collecting, but due to poor management and mangrove destruction, ...
E. coli contaminated drinking water in rural Uganda: Using results to make an impact
(2007)
In January 2006, I worked with Community Based Integrated Nutrition (COBIN) to perform water quality testing and design & distribute health questionnaires to 40 households in the Lyantonde and Kiruhura districts of rural ...
Feasibility study: Comparison of performance status with objective physical activity monitors in lung cancer patients
(2010)
Context: Performance status (PS) is a predictor of response to chemotherapy but difficult to identify in patients with advanced lung cancer. It is measured using the ECOG scale, which relies on simple questions to assign ...