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The Effects of Doa4 and Other Multivesicular-Body Proteins on Brome Mosaic Virus Replication in Yeast
(2008)
Brome Mosaic Virus (BMV) replication was measured in yeast single and double deletion mutants of Doa4 and other proteins in the multivesicular-body (MVB) pathway in order to determine the role of Doa4 and other MVB proteins ...
Cleavage and Polyadenylation Specific Factor 6 (CPSF6): A possible protein mediator for CARM1 and pre-MRNA splicing
(2008)
Coactivated associated methyltransferase 1 (CARM1), an enzyme that regulates cellular processes via arginine methylation, has been suggested to play a role in RNA processing and alternative splicing. The focus of this ...
Defining the PIPKIgamma707/SNX5 interaction and its possible association with E-cadherin
(2008)
E-cadherin, a cell adhesion molecule and tumor suppressor plays an important role in suppressing metastasis of cancers of epithelial origin by acting as the cornerstone of adherens junctions, which facilitate adhesion ...
Inflammatory response and extracellular matrix turnover following pulsed dyed laser treatment of vocal fold and vocal fold fibroblasts
(2008)
The 585-nm pulsed dye laser (PDL) is commonly utilized for the treatment of vascular and epithelial vocal fold lesions; however there are anecdotal reports that it may improve scar outcomes, perhaps by altering extracellular ...
Inhibition of the Escherichia coli replication cycle by a mutant RecA protein
(2008)
Abstract: A conserved [K/R]x[K/R] motif is found at the subunit-subunit interface in bacterial RecA protein filaments. In the Escherichia coli RecA protein, this motif is made up of residues K248 and K250. Both of these ...
The effects of erythropoietin on transferrin receptor concentration in rat duodenum tissue
(2008)
Preliminary studies showed factors contained in human milk retain their mitogenic activity following pasteurization. Iron is critical in cell proliferation in early life. Erythropoietin (Epo), a factor found in human milk, ...
Chronic and acute seizure activity affects NKCC1 and KCC2 expression and alters GABA-induced inhibition in the adult and developing hippocampus
(2008)
Temporal lobe epilepsy is a relatively common nervous system disorder characterized by abnormal activity in the hippocampus, often caused by a decrease in GABA inhibition. GABAA receptors are Cl- ion channels whose effects ...
Characterization of Tau Phosphorylation During the Differentiation of Human Embryonic Stem Cells
(2008)
Alzheimer's disease is the seventh leading cause of death in the United States with an estimated cost of 100 billion dollars. The severity of this neurodegenerative disease is strongly correlated with the number of ...
Mutations in CNGC2 in Arabidopsis thaliana lead to a reduction in fertility due to a sporophytic defect
(2008)
While cyclic nucleotide gated channels (CNGCs) are known to play an important role in sensory transduction in animals, little is known about their functions and the mechanisms by which they act in plants. cngc2 plants ...
Pre-steady state product formation rates for mutant and wild type toluene 4-monooxygenases
(2008)
This study measures the pre-steady state product formation rate for toluene 4-monooxygenase (T4MO). T4MO catalyzes the NADH and O2 dependent hydroxylation of toluene to form p-cresol. By using alternative substrates with ...