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Cleavage and Polyadenylation Specific Factor 6 (CPSF6): A possible protein mediator for CARM1 and pre-MRNA splicing
(2008)
Coactivated associated methyltransferase 1 (CARM1), an enzyme that regulates cellular processes via arginine methylation, has been suggested to play a role in RNA processing and alternative splicing. The focus of this ...
Reduction of androgen induced reactive oxygen species (ROS) production as a method of preventing prostate cancer
(2007)
Prostate cancer is a leading cause of cancer deaths among men and development of a preventative agent is urgently needed. Reactive oxygen species (ROS) are carcinogens and are linked to prostate tumor development. ROS ...
Preneoplastic Lesion Growth in B6.Hcs7C3H 219R8 Congenic Hepatocarcinogen-Sensitive Mus musculus
(2009)
A region of mouse Chromosome 1, called the Hcs7 locus, is involved in the susceptibility to liver carcinogenesis in the inbred mouse strain, C3H/HeJ (C3H). Linkage analysis of a cross between C3H and a strain that is ...
Characterization of ZIIR element of BZLF1 promoter in the context of the whole Epstein - Barr Virus genome
(2007)
Latent infection of Epstein-Barr virus (EBV) is associated with many human cancers. Induction of lytic replication of EBV may lead to destruction of these tumor cells. The viral immediate-early gene, BZLF1, plays a key ...