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Determining the requirement for viral DNA amplification in mediating the reorganization of cellular chromatin during the Epstein-Barr virus lytic cycle
(2023)
We have uncovered how Epstein-Barr virus (EBV) induces the reorganization of cellular chromatin
(ROCC), where host chromatin is compacted and marginated within the nucleus. We tested the role of
EBV lytic DNA amplification ...
The Effect of Alfalfa Perimeter Plantings on Strawberry Pollen Consumption by Syrphidae (Diptera) in Wisconsin
(2023)
Syrphid flies visit flowers to feed on nectar and pollen and provide an important pollination
service in many cropping systems. We previously observed that perimeter plantings of alfalfa
concentrate syrphid populations ...
Investigating the Role of SDHB in Cardiac Regeneration
(2023)
Heart failure is the leading cause of death in the United States. The long wait for heart
transplants and the risk of graft rejection has motivated heart regeneration research to advance
heart failure treatment. Importantly, ...
Investigating Fyv6’s role in splicing through RNA sequencing and selective protein depletion
(2023)
Splicing of pre-mRNAs is an essential process for regulation of eukaryotic gene
expression. Splicing is carried out by the spliceosome, a highly dynamic complex. Mutations
within the spliceosome are responsible for various ...
Do IRX3 and IRX5 Direct Cytoplasm Traffic Between Oocytes During Germline Cyst Breakdown?
(2023)
Poor oocyte quality and a diminished ovarian reserve contribute significantly to female
infertility. The ovarian reserve is determined by the finite supply of primordial follicles a woman
has at birth. Evidence suggests ...
Determining the Role of Energy on Mammary Gland Utilization of Plasma Amino Acid
(2023)
Our overall objective is to investigate nutritional strategies that upregulate signaling pathways of milk protein synthesis directing nitrogen towards milk production, therefore reducing the amount of nitrogen waste entering ...
Analysis of StAR RNA Splicing and Lipid Droplets Composition in MA10 Cells Under Different Stimuli
(2023)
Steroidogenic acute regulatory protein (StAR) is a transport protein which plays a key role in steroidogenesis. Different pathways can activate StAR transcription. cAMP activates PKA which phosphorylates CREB. PKA also ...
Investigating the Binding Specificity of Polymorphic KIR Alleles with Potential Ligands
(2023)
Natural killer (NK) cells are an important part of the immune response and play a
vital role in the defense against viral pathogens. NK cell function is characterized by its
ability to regulate cytotoxicity and modulate ...
Investigation of the Contribution of the Stimulator of Interferon Genes (STING) Pathway to the Type I interferon response in Murine glioblastoma cell lines
(2023)
Glioblastoma Multiforme (GBM) is a potent type of cancer due to its high mortality and aggressive nature with a median survival of 14 months post-diagnosis (1, 2). Immunotherapies are a promising approach to treating GBMs ...
Examining the multi-species impact on the built-space microbiome of a small-scale USDA inspected animal processing facility
(2023)
The global population continues to expand, driving a need for increased food production, including animal-derived proteins from poultry, pork, beef, and lamb. In the US, large-scale processing facilities dominate the meat ...