The omentum is an intra-abdominal fat pad. It is a well-vascularized structure that is sometimes referred to as the "policeman of the abdomen" for its proclivity to adhere to sites of intra-abdominal inflammation or injury. ...

Insect juvenile hormone (JH) and its hemolymph transport protein, juvenile hormone binding protein (JHBP) play key roles in the development of many insects. However, the exact mechanism via which JH and JHBP regulates ...

Pleiotropic drug resistance (PDR) is the resistance to multiple drugs that occurs by upregulating gene expression of ABC (ATP-binding cassette) transporters that transport drug out of the cell. Thakur et al. (2008) ...

Plants have undergone strong selection from herbivory, resulting in diverse physical and chemical defenses. Chemical defenses deter generalist herbivores, but are often tolerated by specialists. Mimulus guttatus (yellow ...

The E3 ligases GRAIL and Cbl-b are necessary for the induction of CD4+ T cell anergy. Using CD4+ T cells from wildtype (WT) and Cbl-b knockout (Cbl-B -/-) mice, we investigated the relationship between GRAIL and Cbl-b. ...

The interaction between salts and nucleic acid bases or aromatic compounds plays an important role in noncovalent biopolymer assembly processes such as DNA and RNA helix formation and protein-nucleic acid interactions. The ...

This project lays the foundation for identifying chemical inducers and inhibitors in swarming cells of Escherichia coli. Swarming is a type of cell surface motility characterized by differentiated bacterial cells that have ...

The identification and quantification of the interactions between hydroxylated solutes and biological macromolecules will aid in the development of solutes, as tools, in a number of biochemical contexts including protein ...

E. coli 0157:H7 is a food pathogen with exceptional tolerance to certain stressful growth conditions. RpoS is a master regulator for bacterial stress adaptation and in particular, for acid resistance genes. The role of ...