Calorie Restriction (CR) without malnutrition extends mean and maximal lifespan in multiple species, although the mechanism is unknown. CR has a dramatic effect on adipose tissue morphology, gene expression and energy ...

Alzheimer's disease is the seventh leading cause of death in the United States with an estimated cost of 100 billion dollars. The severity of this neurodegenerative disease is strongly correlated with the number of ...

Context: Performance status (PS) is a predictor of response to chemotherapy but difficult to identify in patients with advanced lung cancer. It is measured using the ECOG scale, which relies on simple questions to assign ...

BACKGROOUND: Cardiovascular risk factors at mid-life are associated with an increased risk of developing Alzheimer's disease (AD). OBJECTIVE: Determine relationships between baseline dementia risk, cognitive function, CSF ...