Browsing College of Agricultural and Life Sciences Honors and Undergraduate Research Program by Subject "Biochemistry"
Now showing items 1-20 of 51
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Analyzing interactions between the GV1 Cell Line, Juvenile Hormone, and Juvenile Hormone Binding Protein
(2011)Insect juvenile hormone (JH) and its hemolymph transport protein, juvenile hormone binding protein (JHBP) play key roles in the development of many insects. However, the exact mechanism via which JH and JHBP regulates ... -
Attempts to analyze the RNA-binding specificity of the C. elegans RNP-8 protein
(2010)Cytoplasmic polyadenylation is a key mechanism of gene regulation in all eukaryotes. The C. elegans GLD-2 protein provides the catalytic activity for a cytoplasmic poly(A) polymerase, but GLD-2 must partner with another ... -
Bioassay-guided purification and characterization of anti-inflammatory components in Cinnamomum burmannii
(2010)Excessive inflammatory response is implicated in many diseases such as arthritis, atherosclerosis, and cardiomyopathy. Previous studies have found that several cinnamon species could exhibit anti-inflammatory activities. ... -
Characterization of Putative RpoS-regulated Outermembrane Proteins Slp and OmpX in Escherichia coli 0157:H7
(2012)E. coli 0157:H7 is a food pathogen with exceptional tolerance to certain stressful growth conditions. RpoS is a master regulator for bacterial stress adaptation and in particular, for acid resistance genes. The role of ... -
Characterization of Tau Phosphorylation During the Differentiation of Human Embryonic Stem Cells
(2008)Alzheimer's disease is the seventh leading cause of death in the United States with an estimated cost of 100 billion dollars. The severity of this neurodegenerative disease is strongly correlated with the number of ... -
Characterization of ZIIR element of BZLF1 promoter in the context of the whole Epstein - Barr Virus genome
(2007)Latent infection of Epstein-Barr virus (EBV) is associated with many human cancers. Induction of lytic replication of EBV may lead to destruction of these tumor cells. The viral immediate-early gene, BZLF1, plays a key ... -
Chronic and acute seizure activity affects NKCC1 and KCC2 expression and alters GABA-induced inhibition in the adult and developing hippocampus
(2008)Temporal lobe epilepsy is a relatively common nervous system disorder characterized by abnormal activity in the hippocampus, often caused by a decrease in GABA inhibition. GABAA receptors are Cl- ion channels whose effects ... -
Cleavage and Polyadenylation Specific Factor 6 (CPSF6): A possible protein mediator for CARM1 and pre-MRNA splicing
(2008)Coactivated associated methyltransferase 1 (CARM1), an enzyme that regulates cellular processes via arginine methylation, has been suggested to play a role in RNA processing and alternative splicing. The focus of this ... -
Defining the PIPKIgamma707/SNX5 interaction and its possible association with E-cadherin
(2008)E-cadherin, a cell adhesion molecule and tumor suppressor plays an important role in suppressing metastasis of cancers of epithelial origin by acting as the cornerstone of adherens junctions, which facilitate adhesion ... -
Determining the minimal nutrient requirements for the swarming phenotype in Escherichia coli and other swarming bacterial species
(2010)This project lays the foundation for identifying chemical inducers and inhibitors in swarming cells of Escherichia coli. Swarming is a type of cell surface motility characterized by differentiated bacterial cells that have ... -
E. coli contaminated drinking water in rural Uganda: Using results to make an impact
(2007)In January 2006, I worked with Community Based Integrated Nutrition (COBIN) to perform water quality testing and design & distribute health questionnaires to 40 households in the Lyantonde and Kiruhura districts of rural ... -
The effect of neuropeptides on growth and function of bovine articular chondrocytes
(2007)Cartilage injury is a central issue in orthopedics to which there is no known physiological treatment. Neuropeptides playa role in the proliferative and reparative processes of many tissue types, but little is known about ... -
The effects of 1,25 D3 on the mouse osteopontin promoter
(2007)Vitamin D (1,25 D3) is an important transcriptional regulator of many genes including our gene of interest, osteopontin. Osteopontin is a known regulator of bone calcification and mineralization and is involved in signaling ... -
The Effects of Doa4 and Other Multivesicular-Body Proteins on Brome Mosaic Virus Replication in Yeast
(2008)Brome Mosaic Virus (BMV) replication was measured in yeast single and double deletion mutants of Doa4 and other proteins in the multivesicular-body (MVB) pathway in order to determine the role of Doa4 and other MVB proteins ... -
The effects of erythropoietin on transferrin receptor concentration in rat duodenum tissue
(2008)Preliminary studies showed factors contained in human milk retain their mitogenic activity following pasteurization. Iron is critical in cell proliferation in early life. Erythropoietin (Epo), a factor found in human milk, ... -
Engineering of maltose-binding protein to employ a poly-arginine tag and improve protein purification
(2007)Maltose binding protein (MBP), a solubility-enhancing fusion protein, has demonstrated great success in the application of protein purification when fused to a protein of interest. It has already been engineered to include ... -
Exploration of the relationship between GRAIL and Cbl-b
(2010)The E3 ligases GRAIL and Cbl-b are necessary for the induction of CD4+ T cell anergy. Using CD4+ T cells from wildtype (WT) and Cbl-b knockout (Cbl-B -/-) mice, we investigated the relationship between GRAIL and Cbl-b. ... -
Exploring the role of Na+\H+ exchanger in neonatal brain injuring following hypoxia-ischemia
(2010)We investigated the role of Na+/H+ exchanger isoform 1 (NHE-1) in neonatal hypoxia ischemia (HI). HI was induced by unilateral ligation of the left common carotid artery is postnatal day 9 (PN) mice, and subsequent exposure ... -
Functional differences between the yeast Hsp70 molecular chaperones Ssbl and Ssb2
(2011)Protein folding is a complex process that is mediated in the cell by molecular chaperones. Errors in protein folding can lead to aggregation of rnisfolded proteins, causing diseases such as Alzheimer's disease and ...