Browsing College of Agricultural and Life Sciences Honors and Undergraduate Research Program by Title
Now showing items 14-33 of 199
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Chamber-related variation in phosphorylation state of cardiac troponin revealed by high resolution top-down mass spectrometry
(2010)Cardiac troponin complex (cTn) is a key regulator of Ca-2+- mediated cross-bridge cycling in cardiac muscle. Post-translational modifications, especially phosphorylation of cTn, are major mechanisms in modulation of ... -
Characterization of my18, a mutant exhibiting abnormal expression of the C. elegans polycystic kidney disease gene
(2007)Autosomal Dominant Polycystic Kidney Disease (ADPKD) is a common genetic disorder affecting 1/400 to 1/800 individuals in the population. Mutations in the human genes PKD1 and PKD2, which encode Polycystin-l (PC-I) and ... -
Characterization of nuclear RNAi defective mutants in C. elegans
(2008)Proper gene expression is crucial for all cellular processes, and changes in normal gene expression has been implicated in a number of human diseases, including asthma, heart disease, and cancer (Guajardo 2005, Tan 2002, ... -
Characterization of Putative RpoS-regulated Outermembrane Proteins Slp and OmpX in Escherichia coli 0157:H7
(2012)E. coli 0157:H7 is a food pathogen with exceptional tolerance to certain stressful growth conditions. RpoS is a master regulator for bacterial stress adaptation and in particular, for acid resistance genes. The role of ... -
Characterization of Tau Phosphorylation During the Differentiation of Human Embryonic Stem Cells
(2008)Alzheimer's disease is the seventh leading cause of death in the United States with an estimated cost of 100 billion dollars. The severity of this neurodegenerative disease is strongly correlated with the number of ... -
Characterization of ZIIR element of BZLF1 promoter in the context of the whole Epstein - Barr Virus genome
(2007)Latent infection of Epstein-Barr virus (EBV) is associated with many human cancers. Induction of lytic replication of EBV may lead to destruction of these tumor cells. The viral immediate-early gene, BZLF1, plays a key ... -
Characterizing the nucleotide-binding domain of Escherichia coli HscA, a specialized Hsp70 chaperone in Fe-S cluster biogenesis
(2014-05)Proteins from the ISC operon of E. coli constitute the machinery used for the synthesis of iron-sulfur clusters and their delivery to recipient apo-proteins. [2Fe-2S] cluster transfer from the holo-scaffold protein lscU ... -
Chronic and acute seizure activity affects NKCC1 and KCC2 expression and alters GABA-induced inhibition in the adult and developing hippocampus
(2008)Temporal lobe epilepsy is a relatively common nervous system disorder characterized by abnormal activity in the hippocampus, often caused by a decrease in GABA inhibition. GABAA receptors are Cl- ion channels whose effects ... -
Cleavage and Polyadenylation Specific Factor 6 (CPSF6): A possible protein mediator for CARM1 and pre-MRNA splicing
(2008)Coactivated associated methyltransferase 1 (CARM1), an enzyme that regulates cellular processes via arginine methylation, has been suggested to play a role in RNA processing and alternative splicing. The focus of this ... -
Community-Level Effects of Garlic Mustard Invasion on Wisconsin Forest Communities
(2008)Community ecologists frequently assume that impacts of invasive species are negative, but this assertion is poorly supported in the literature. To test this, we surveyed 10 sites invaded with the biennial herb Alliaria ... -
Comparing Measures of Immunity and Health Status in the Golden-winged Warbler (Vermivora chrysoptera) X Blue-winged Warbler (V. cyanoptera) Hybridization System
(2011)I report the results of the first immunological tests in the Golden-winged Warbler (Vermivora chrysoptera) X Blue-winged Warbler (V: cyanoptera) hybridization complex. The study intended to investigate whether the Blue-winged ... -
Comparison of non-heme liver iron and iron metabolism protein levels in superoxide dismutase 1 knock-out mice versus superoxide dismutase 1 wild-type mice
(2007)Iron is an important micronutrient that is necessary for multiple cellular functions. However, iron levels must be tightly regulated in order to prevent iron-deficiency and iron-toxicity. There are many proteins involved ... -
Defining the molecular determinants required for RNA binding functions of the Bicaudal-C (Bicc1) translational repressor protein
(2020-05)Bicaudal-C (Bicc1) is an RNA binding protein that functions as translational repressor in all animal species. Its repression activities are required for a multitude of biological processes such as guiding the earliest steps ... -
Defining the PIPKIgamma707/SNX5 interaction and its possible association with E-cadherin
(2008)E-cadherin, a cell adhesion molecule and tumor suppressor plays an important role in suppressing metastasis of cancers of epithelial origin by acting as the cornerstone of adherens junctions, which facilitate adhesion ... -
Delta-opioid receptor (DOR) activation prolongs respiratory motor output during oxygen-glucose deprivation (OGD) in neonatal rat spinal cord in vitro
(2007)Severe reduction of blood flow to the brain results in oxygen-glucose deprivation (OGD) and neuronal damage. DOR activation is neuroprotective during OGD in the cerebellum and cortex, but it is not known whether DOR ... -
Determining the impacts of residential lakeshore development and various physical factors on largemouth bass (Micropterus salmoides) growth rates
(2007)Development of residential lakeshore properties can have several effects on aquatic ecosystems including the thinning of littoral coarse woody habitat. Previous studies have shown that reduction of littoral coarse woody ... -
Determining the minimal nutrient requirements for the swarming phenotype in Escherichia coli and other swarming bacterial species
(2010)This project lays the foundation for identifying chemical inducers and inhibitors in swarming cells of Escherichia coli. Swarming is a type of cell surface motility characterized by differentiated bacterial cells that have ... -
Determining the requirement for viral DNA amplification in mediating the reorganization of cellular chromatin during the Epstein-Barr virus lytic cycle
(2023)Steroidogenic acute regulatory protein (StAR) is a transport protein which plays a key role in steroidogenesis. Different pathways can activate StAR transcription. cAMP activates PKA which phosphorylates CREB. PKA also ... -
Determining the Role of Energy on Mammary Gland Utilization of Plasma Amino Acid
(2023)Our overall objective is to investigate nutritional strategies that upregulate signaling pathways of milk protein synthesis directing nitrogen towards milk production, therefore reducing the amount of nitrogen waste entering ...