Parametric Studies of Melt Electrospinning Poly ?(caprolactone) Fibers for Tissue Engineering Applications

File(s)
Date
2013-03-25Author
Ko, Junghyuk
K. Mohtaram, Nima
Lee, Patrick C.D.
Willerth, Stephanie M.
Jun, Martin B.
Publisher
8th International Conference on MicroManufacturing (ICOMM 2013)
Metadata
Show full item recordAbstract
The process of electrospinning has received remarkable amount of attention as this technique can be used to fabricate suitable scaffolds for cells. In order to control morphology of scaffold, parametric studies are necessary in customized melt electrospinning. In this study, we demonstrate that fiber diameter could be controlled by customized nozzle and parameters which are temperature, voltage, and distance influence to fiber diameter. Moreover, we culture and seed murine CE3 stem cells derived from D3 embryonic stem cell line on fabricated scaffolds. Overall, scaffold controlled by parameter studies holds a promising strategy for superb cell attachment and proliferation.
Subject
tissue engineering
scaffolds
melt electrospinning
Permanent Link
http://digital.library.wisc.edu/1793/65300Type
Conference Paper
Citation
ICOMM 2013 No. 15