Comparison of Coarse-Grained and Atomistic-Level Simulations for Aminoacyl-tRNA Synthetases

File(s)
Date
2012-04Author
Strom, Alexander M.
Tadayon, Stephanie N.
Yang, Yer
Advisor(s)
Bhattacharyay, Sudeep
Hati, Sanchita
Metadata
Show full item recordAbstract
Aminoacyl-tRNA synthetases (AARSs) are a group of multi-domain enzymes responsible for catalyzing the covalent attachment of an amino acid to the cognate tRNA forming an aminoacyl-tRNA. In this study, both atomistic-level and coarse-grained dynamic simulations were conducted on Escherichia coli methionyl-tRNA synthetase (Ec MetRS), Enterococcus faecalis prolyl-tRNA synthetase (Ef ProRS), and Thermus Thermophilus leucyl-tRNA synthetase (Tt LeuRS).
Subject
Chemistry--Computer simulation
Aminocycl-tRNA synthetases
Posters
Permanent Link
http://digital.library.wisc.edu/1793/63154Type
Presentation
Description
Color poster with text, diagrams, charts, images, and tables.