Testing D1 dopamine receptors and glutamate combined effects on brain stimulation reward in the extended amygdala

dc.contributor.advisor	Waraczynski., Meg
dc.contributor.author	Stoehr, Michele
dc.date.accessioned	2012-07-05T15:39:27Z
dc.date.available	2012-07-05T15:39:27Z
dc.date.issued	2012
dc.identifier.uri	http://digital.library.wisc.edu/1793/61636
dc.description	This file was last viewed in Adobe Reader X	en
dc.description.abstract	Purpose: To further understand the neural mechanisms underlying evaluation of rewarding stimuli in the mammalian brain. More specifically, to examine the effects of dopamine and glutamate manipulations in the central aspect of the sublenticular extended amygdala (SLEAc) on reward evaluation. Dopamine (DA) and glutamate (GLU) interact and are involved in reward evaluation. Our lab found a decrease in reward value when dopamine receptor 2 (D2) agonist/glutamate blocker combination solution was microinjected into the SLEAc but not the nucleus accumbens shell. Similar research suggests this effect may be more pronounced if dopamine receptor 1 (D1) drugs rather than D2 drugs are microinjected with GLU drugs.	en
dc.language.iso	en_US	en
dc.subject	Neurotransmitter receptors	en
dc.subject	Dopamine	en
dc.subject	Glutamic acid	en
dc.subject	Brain stimulation	en
dc.subject	Amygdaloid body	en
dc.subject	Brain	en
dc.title	Testing D1 dopamine receptors and glutamate combined effects on brain stimulation reward in the extended amygdala	en
dc.type	Presentation	en