Browsing UW Hospital and Clinics Materials by Title

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Differential internalization of hu14.18-IL2 immunocytokine by NK and tumor cell: impact on conjugation, cytotoxicity, and targeting

Reisfeld, RA; Gillies, SD; Rakhmilevich, AL; Yamane, B; Hank, JA; Gubbels, JA; Patankar, MS; Buhtoiarov, TN; Gan, J; Buhtoiarov, IN; Neal, ZC; Sondel, PM (2011-04)

The hu14.18-IL2 (EMD 273063) IC, consisting of a GD(2)-specific mAb genetically engineered to two molecules of IL-2, is in clinical trials for treatment of GD(2)-expressing tumors. Anti-tumor activity of IC in vivo and in ...
Genotypes of NK cell KIR Receptors, Their Ligands, and Fc? Receptors in the Response of Neuroblastoma Patients to Hu14.18-IL2 Immunotherapy

Maris, JM; Seeger, RC; London, WB; DeSantes, KB; Gadbaw, B; Yang, R; Reisfeld, RA; Gillies, SD; Shusterman, S; Kim, K; Seo, S; Gan, J; Lorentzen, D; Kolesar, J; Hank, JA; Delgado, DC; Sondel, Paul (2010-12-01)

Response to immunocytokine (IC) therapy is dependent on natural killer cells in murine neuroblastoma (NBL) models. Furthermore, killer immunoglobulin-like receptor (KIR)/KIR-ligand mismatch is associated with improved ...
Reducing Isolation: an adult cystic fibrosis support group

Unknown author (2007)

In 2004 the UWHC Pulmonary Care Center initiated an adult support group -- setting forth clear infection control standards. Two health professionals, a nurse and social worker, provide structure for the group. The group ...