MUC1 Tandem Repeat Structural Studies Using Nuclear Magnetic Resonance Spectroscopy.
Date
2009-02-09Author
Weyer, Jeremy J.
Rose, Daniel H.
Advisor(s)
Yang, Thao
Metadata
Show full item recordAbstract
In this project we employed the Solid Phase Peptide Synthesis Method to synthesize mucin peptides. The methodology for the synthesis of linear and cyclic mucin peptides are presented here. The amino acid sequence of the mucin peptides were derived from the tandem repeat of the mucin-1 (MUC-1) protein. 2D 1H NMR is employed to study the structures of these peptides. Subsequent studies will focus on the binding properties of mucin peptides to monoclonal antibody expressed against tandem repeat of the MUC-1 protein.
Subject
MUC-1 protein
Mucins--Synthesis
Peptides--Synthesis
Nuclear magnetic resonance spectroscopy
Posters
Permanent Link
http://digital.library.wisc.edu/1793/32195Type
Presentation
Description
Color poster with text and diagrams describing research conducted by Daniel H. Rose and Jeremy J. Weyer, advised by Thao Yang.