How Does Amphotericin B Activate Inflammatory Gene Expression in Monocytic Cells?
Date
2009-01-09Author
Donath, Michael J.
Advisor(s)
Turtinen, Lloyd W.
Metadata
Show full item recordAbstract
Amphotericin B is an antifungal drug used to treat systemic fungal infection because of its ability to form a pore complex with ergosterolin the fungal cell membrane. The side effects of this drug include fever, shaking, chills, hypotension, nausea, vomiting, and nephrotoxicity. This study investigates the possible mechanism that leads to the activation of proinflammatory genes during Amphotericin B treatments.
Subject
Amphotericin B
Monocytes
Inflammation
Posters
Permanent Link
http://digital.library.wisc.edu/1793/31820Description
Color poster with text, illustrations, and graphs describing research conducted by Michael J. Donath, advised by Lloyd W. Turtinen.