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    How Does Amphotericin B Activate Inflammatory Gene Expression in Monocytic Cells?

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    File(s)
    DonathSpr08.pdf (3.070Mb)
    DonathSpr08.pptx (1.428Mb)
    Date
    2009-01-09
    Author
    Donath, Michael J.
    Advisor(s)
    Turtinen, Lloyd W.
    Metadata
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    Abstract
    Amphotericin B is an antifungal drug used to treat systemic fungal infection because of its ability to form a pore complex with ergosterolin the fungal cell membrane. The side effects of this drug include fever, shaking, chills, hypotension, nausea, vomiting, and nephrotoxicity. This study investigates the possible mechanism that leads to the activation of proinflammatory genes during Amphotericin B treatments.
    Subject
    Amphotericin B
    Monocytes
    Inflammation
    Posters
    Permanent Link
    http://digital.library.wisc.edu/1793/31820
    Description
    Color poster with text, illustrations, and graphs describing research conducted by Michael J. Donath, advised by Lloyd W. Turtinen.
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    • Student Research Day

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