Now showing items 1-8 of 8
Metal Sequestration During Aggregation Based Crystal Growth
This project is focused on determining how associated metals of environmental concern (especially Pb) behave during aggregationbased crystal growth as a function of increasing Crystallinity Index (CI).
Synthesis and Antibody Binding Study of MUC1 Mucin Peptides with Unnatural Backbones
The MUC-1 mucin is a heavily glycosylated transmembrane protein found on the apical surface of epithelial cells with a short cytoplasmic end and a longer extracellular domain consisting of multiple 20-amino acid tandem ...
Computational Docking of Mucin Peptide Derivatives with SM3 Antibody
The crystal structure of the mucin monoclonal antibody SM3 complexed with a 13 amino acid MUC1 mucin peptide was determined. The high selectivity of the SM3 antibody to the aberrant carbohydrate cancer mucin peptide suggests ...
Use of Geometrical Docking Algorithm to Explore Species Specific Differences in Proyl-tRNA Synthetases
Prolyl-tRNA synthetases belong to a class of enzymes that play a pivotal role in the protein synthesis. These enzymes are responsible for attaching the amino acid, proline, to the 3’ end of the prolyl-tRNA. The structures ...
Studying the Effects of Varying pH and Temperature on the Smart Polymer mPEG-block-PDMAEMA
“Smart polymers” change their mechanical properties in response to changes in stimuli, such as pH, temperature, and polymer concentration. We chose to focus on the viscoelastic properties when determining the effects of ...
Flipping the General Chemistry Laboratory : Increasing Student Engagement by Enhancing Self-Directed Learning
The goal of this study is two-fold: to gather information about the impact of flipped and traditional teaching modes on student understanding of course material, as well measuring students' attitudes about chemistry. Our ...
Synthesis of Mucin Peptide Epitopes
The MUC-1 mucin is a heavily glycosylated transmembrane protein found on the apical surface of the epithelial cells that contains a short cytoplasmic end and a long extracellular domain consisting of multiple 20-amino acid ...
Synthesis of Smart Polymer-Grafted Silica and Confocal Microscopy
The purpose of this study is to synthesize and characterize smart polymer-grafted colloidal silica particles in order to better understand and tune the smart characteristics and properties.