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Investigation of Angiogenic Mechanisms Involved in Omentum Transplantation
(2017-06-13)
The omentum is an intra-abdominal fat pad. It is a well-vascularized structure that is sometimes referred to as the "policeman of the abdomen" for its proclivity to adhere to sites of intra-abdominal inflammation or injury. ...
Analyzing interactions between the GV1 Cell Line, Juvenile Hormone, and Juvenile Hormone Binding Protein
(2011)
Insect juvenile hormone (JH) and its hemolymph transport protein, juvenile hormone
binding protein (JHBP) play key roles in the development of many insects. However, the exact mechanism via which JH and JHBP regulates ...
Pleiotropic drug resistance activation via over expression of Zuo1
(2010)
Pleiotropic drug resistance (PDR) is the resistance to multiple drugs that occurs by upregulating gene expression of ABC (ATP-binding cassette) transporters that transport drug out of the cell. Thakur et al. (2008) ...
Herbivory defense in Mimulus quttatus (yellow monkeyflower): consequences for generalist and specialist herbivores
(2012)
Plants have undergone strong selection from herbivory, resulting in diverse physical and
chemical defenses. Chemical defenses deter generalist herbivores, but are often tolerated by specialists. Mimulus guttatus (yellow ...
Exploration of the relationship between GRAIL and Cbl-b
(2010)
The E3 ligases GRAIL and Cbl-b are necessary for the induction of CD4+ T cell anergy. Using CD4+ T cells from wildtype (WT) and Cbl-b knockout (Cbl-B -/-) mice, we investigated the relationship between GRAIL and Cbl-b. ...
Predicting and Interpreting the Hofmeister Effects of Different Salts with Nucleic Bases and Aromatic Compounds Using Solubility Assay
(2017-06-13)
The interaction between salts and nucleic acid bases or aromatic compounds plays an important role in noncovalent biopolymer assembly processes such as DNA and RNA helix formation and protein-nucleic acid interactions. The ...
Determining the minimal nutrient requirements for the swarming phenotype in Escherichia coli and other swarming bacterial species
(2010)
This project lays the foundation for identifying chemical inducers and inhibitors in swarming cells of Escherichia coli. Swarming is a type of cell surface motility characterized by differentiated bacterial cells that have ...
Interpretation of Effects of Hydroxylated Solutes on DNA Hairpin Stability
(2012)
The identification and quantification of the interactions between hydroxylated solutes and biological macromolecules will aid in the development of solutes, as tools, in a number of biochemical contexts including protein ...
Characterization of Putative RpoS-regulated Outermembrane Proteins Slp and OmpX in Escherichia coli 0157:H7
(2012)
E. coli 0157:H7 is a food pathogen with exceptional tolerance to certain stressful growth conditions. RpoS is a master regulator for bacterial stress adaptation and in particular, for acid resistance genes. The role of ...