http://digital.library.wisc.edu/1793/8334 2026-03-08T14:28:52Z http://digital.library.wisc.edu/1793/96510 Using Connected Intelligent Transportation to Enhance Vulnerable Road User Safety Huang, Zilin; Wan, Zhengyang; Sheng, Zihao; Ahn, Sue; Noyce, David; Chen, Sikai This project leverages connected intelligent transportation technologies to enhance the safety of vulnerable road users (VRUs) within evolving urban road systems. This project targets three fundamental barriers: the lack of high-fidelity experimental platforms, localization failures in GNSS-denied areas, and insufficient trajectory prediction for heterogeneous agents. Our goal is to develop an integrated cooperative system that combines virtual reality, wireless communication, and physics-informed learning. To achieve this, we develop Sky-Drive, a distributed multi -agent simulation platform that enables human -in-the-loop interaction testing. Furthermore, the project implements a cellular Vehicle-to-Everything (C-V2X)-based cooperative localization framework to ensure lane-level accuracy and a kinematics-aware multigraph attention network for precise motion forecasting. The output of this project provides a comprehensive technological foundation for enabling the safe and equitable coexistence of autonomous vehicles (AVs) and VRUs in mixed traffic environments. 2025-12-31T00:00:00Z http://digital.library.wisc.edu/1793/96509 Using Connected Intelligent Transportation to Enhance Vulnerable Road User Safety Huang, Zilin; Wan, Zhengyang; Sheng, Zihao; Ahn, Sue; Noyce, David; Chen, Sikai This project leverages connected intelligent transportation technologies to enhance the safety of vulnerable road users (VRUs) within evolving urban road systems. This project targets three fundamental barriers: the lack of high-fidelity experimental platforms, localization failures in GNSS-denied areas, and insufficient trajectory prediction for heterogeneous agents. Our goal is to develop an integrated cooperative system that combines virtual reality, wireless communication, and physics-informed learning. To achieve this, we develop Sky-Drive, a distributed multi -agent simulation platform that enables human -in-the-loop interaction testing. Furthermore, the project implements a cellular Vehicle-to-Everything (C-V2X)-based cooperative localization framework to ensure lane-level accuracy and a kinematics-aware multigraph attention network for precise motion forecasting. The output of this project provides a comprehensive technological foundation for enabling the safe and equitable coexistence of autonomous vehicles (AVs) and VRUs in mixed traffic environments. 2025-12-31T00:00:00Z http://digital.library.wisc.edu/1793/96508 Traumatic brain injury on-a-chip: a microfluidic device for the compression of cortical spheroids Araiza Canizales, Mauricio; McGhee, Alexander; Wan, Yang; Zhang, Jing; González-Cruz, Rafael D.; Hoffman-Kim, Diane; Kesari, Haneesh; Franck, Christian Traumatic brain injury (TBI) affects more than 4.6 million people annually in the United States, with the true numbers of mild TBI (mTBI) likely much higher due to insufficient detection and diagnosis methods. Some of the current challenges for successfully detecting mTBIs include the lack of patient symptoms, and the lack of robust biomarkers for its diagnosis. While the quest for mTBI biomarkers remains an active area of research, the inherent low concentrations and our lack in understanding of the temporal evolution of its parenchymal release pose a significant hurdle to the adoption of blood or saliva-borne biomarkers for injury diagnosis. Three-dimensional neuro-glia- and organoid cell culture models offer an opportunity to model TBI and screen for injury biomarker expression profiles. Yet there remains a shortage of lab-on-a-chip platforms capable of monitoring the evolution of injury biomarkers onset using both imaging and extraction based detection approaches in the same culture platform. In this study, we developed a novel lab-on-a-chip, three-layer microfluidic device capable of reproducibly injuring cortical spheroids to model TBI in vitro. The device can be operated stand-alone with a single pump or straightforwardly integrated with common laboratory microscopes to facilitate real-time imaging access. To demonstrate its applicability for TBI research, compression of cortical spheroids was performed at a strain of 25% and a fixed strain rate of 3.125 s-1 as it is comparable to rates of mild TBI. Assessment of cell viability after 24 hours revealed that the impacted samples, on average, exhibited up to 8% cell death. Additionally, by leveraging a simple push-pull perfusion method, non-impacted samples could be exposed to culture media from injured organoids on the same chip, which also resulted in increased cell death 24 hours later. These findings demonstrated the capability of this device as a viable in vitro platform of TBI, which should lend itself to investigations of TBI and other diseases. 8-bit tiff confocal images of EthD-1 and Hoechst channels, as well as the processed masks used for cell death quantification. 2026-01-01T00:00:00Z http://digital.library.wisc.edu/1793/96506 Oral History Interview, Mark Dorman (2609) Dorman, Mark In his January 2026 interview with Troy Reeves, Mark Dorman discusses his time as a UW-Madison undergraduate student beginning in 1972. Before coming to UW-Madison, Dorman enlisted in the Navy in 1968 and was released in 1971 as a conscientious objector. He shares about his decision to attend UW-Madison, his father’s disapproval of the university, how he paid for school, and his experience as a student not attending UW-Madison straight from high school. He contrasts UW-Madison’s courses with those of the Navy, finding collegiate courses lower stakes, more welcoming, and less challenging. Dorman studied journalism in the public relations segment and was in the Integrated Liberal Studies Program. He shares memories and anecdotes of professors and courses of these programs. Dorman worked part-time as a security guard. He discusses heightened security at WARF, which housed the Army Math Research Center after the bombing of Sterling Hall. Other topics he covers include enrollment, protests, student life and entertainment, and work ethic. To close out the interview, Dorman summarizes his 48 years of state service, including his internship in public relations for UW Hospitals and his jobs investigating Medicare and investment fraud. This interview was conducted for inclusion into the UW-Madison Class Reunion Project of UW-Madison Archives and Record Management Oral History Program. In his January 2026 interview with Troy Reeves, Mark Dorman discusses his time as a UW-Madison undergraduate student beginning in 1972. To learn more about this oral history, download & review the index first (or transcript if available). It will help determine which audio file(s) to download & listen to. 2026-01-08T00:00:00Z