Tanscriptome comparison of ionizing radiation resistant strain of Escherichia coli, CB2000, and naturally occurring strain of Escherichia coli, Founder

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Author(s): Tan, Meng Kwang Marcus
Advisor(s): Cox, Michael M.
Date: 2007
Subject(s): Biochemistry
Abstract: CB2000 is a strain of Escherichia coli (E. coli) that is extremely resistant to ionizing radiation. It was derived from a colony, referred to as the founder strain, isolated from naturally occurring Escherichia coli K12 MG1655. Using microarray technology developed by Affymetrix, a transcriptome comparison was done on CB2000 and Founder to determine the gene(s) that are differentially expressed in CB2000. A large number of genes which are involved in metabolism, transport and stress response were identified to display changes in expression levels in CB2000 when compared to Founder.
Description: 15 p.
Permanent link: http://digital.library.wisc.edu/1793/7953
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