Browsing Biochemistry Honors Theses and Research Papers by Title
Now showing items 34-53 of 84
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A genetic approach to understanding co-regulated MAPK genes in Arabidopsis thaliana
(2007)Mitogen-activated protein kinase (MAPK) signaling cascades connect cellular signal and gene transcription in cells. The pathway can regulate cell division, cell growth, and other pathways in eukaryotes. We used the ... -
Genetic studies of the velC gene required for proper sexual development in Aspergillus nidulans
(2010)VelC is required for the proper fungal development in Aspergillus nidulans. Velvet proteins, VeA, VosA, VelB, and VelC, are a new protein family in many filamentous fungi. They regulate fungal development and secondary ... -
Herbivory defense in Mimulus quttatus (yellow monkeyflower): consequences for generalist and specialist herbivores
(2012)Plants have undergone strong selection from herbivory, resulting in diverse physical and chemical defenses. Chemical defenses deter generalist herbivores, but are often tolerated by specialists. Mimulus guttatus (yellow ... -
Identification of the Functional Domains of Arabidopsis FLS2
(2007)Arabidopsis FLS2 is a leucine-rich repeat (LRR) transmernbrane receptor-kinase that recognizes bacterial flagellin and induces plant innate immune responses. Flg22 is a 22 amino acid peptide based on a sequence of flagellin ... -
Identification of two binding partners for the bacterial actin homolog MreB
(2007)A distinguishing characteristic of prokaryotes was long thought to be the lack of a cytoskeleton similar to eukaryotes consisting of actin filaments, microtubules, and intermediate filaments. However, recent work has shown ... -
Immune cell-ovarian tumor cell adhesion through MUC16 and immunocytokine
(2010)Natural killer (NK) cells are immune cell types that function normally to eliminate tumor cells by forming an immune synapse. However, we have shown that the presence of mucin, MUC16, on the surface of epithelial ovarian ... -
Impact of flanking residue modifications on binding specificity of H3K9 methylation reader; Dppa3
(2015-05-06)Somatic cells can be converted to an embryonic stem cell-like state by transcription factor-mediated reprogramming. These induced pluripotent stem cells (iPSCs), like ESCs, have the ability to divide indefinitely and ... -
Improving the Production of Terpenes by Recombination of 1-Deoxy-D-Xylulose 5-Ph
(2020-05)None provided -
In vitro screenings predict polymer ability to facilitate RNAi through its use as a delivery vehicle of siRNA
(2009)Gene therapy techniques have emerged in recent decades as a method of combating genetic disorders. One prospective branch of gene therapy is using RNA Interference (RNAi) to regulate gene expression. RNAi employs small ... -
Inflammatory response and extracellular matrix turnover following pulsed dyed laser treatment of vocal fold and vocal fold fibroblasts
(2008)The 585-nm pulsed dye laser (PDL) is commonly utilized for the treatment of vascular and epithelial vocal fold lesions; however there are anecdotal reports that it may improve scar outcomes, perhaps by altering extracellular ... -
Inhibition of the Escherichia coli replication cycle by a mutant RecA protein
(2008)Abstract: A conserved [K/R]x[K/R] motif is found at the subunit-subunit interface in bacterial RecA protein filaments. In the Escherichia coli RecA protein, this motif is made up of residues K248 and K250. Both of these ... -
Interpretation of Effects of Hydroxylated Solutes on DNA Hairpin Stability
(2012)The identification and quantification of the interactions between hydroxylated solutes and biological macromolecules will aid in the development of solutes, as tools, in a number of biochemical contexts including protein ... -
Investigating Fyv6’s role in splicing through RNA sequencing and selective protein depletion
(2023)Splicing of pre-mRNAs is an essential process for regulation of eukaryotic gene expression. Splicing is carried out by the spliceosome, a highly dynamic complex. Mutations within the spliceosome are responsible for various ... -
Investigating the inhibitory mechanism of aketoglutarate analogues towards human collagen prolyl 4-hydroxylase
(2014)Collagen is a structural protein essential in wound healing and the formation of connective tissues in humans. Despite its importance, overproduction of collagen can be a potential threat to human life. Production of ... -
Investigation of Angiogenic Mechanisms Involved in Omentum Transplantation
(2017-06-13)The omentum is an intra-abdominal fat pad. It is a well-vascularized structure that is sometimes referred to as the "policeman of the abdomen" for its proclivity to adhere to sites of intra-abdominal inflammation or injury. ... -
Investigation of plant translation initiation factor modulation by Triticum mosaic virus
(2015-05-15)Viruses have evolved unique strategies to take over the cellular protein synthesis machinery of their host for efficient infection. Although viruses cause serious economic damage to agricultural crops, little is known ... -
Investigation of the Genome-Wide Distribution of Histone Variant H3.3
(2020-05)Epigenetic regulation via loci-specific deposition of variant histone proteins is important for genome stability and regulation of gene expression. Replication-independent histone variant H3.3 has been implicated in ... -
Isolation and characterization of Drosophila melanogaster central processing mutants
(2007)The aim of this study is to isolate and characterize mutant fruit flies (Drosophila melanogaster) which are defective in central processing, with the ultimate goals of! finding the genes necessary for this process to ... -
Large scale production of stable hemolymph juvenile hormone binding protein
(2009)To better understand the pathways of the insect juvenile hormone (JH) action, milligram amounts of pure hemolymph juvenile hormone binding protein (hJHBP) are required. Hence the goal of this study is to scale up the system ... -
Measurement of The ADCK3 Transmembrane Helix Self-Association In Escherichia Coli Via the TOXCAT Assay
(2014)The interaction of a-helices in the transmembrane region of certain proteins is important for the function of these proteins. The goal of our project is to study the self-association propensity of the transmembrane region ...