Browsing Biochemistry Honors Theses and Research Papers by Title
Now showing items 19-38 of 84
-
The effect of neuropeptides on growth and function of bovine articular chondrocytes
(2007)Cartilage injury is a central issue in orthopedics to which there is no known physiological treatment. Neuropeptides playa role in the proliferative and reparative processes of many tissue types, but little is known about ... -
The Effects of Doa4 and Other Multivesicular-Body Proteins on Brome Mosaic Virus Replication in Yeast
(2008)Brome Mosaic Virus (BMV) replication was measured in yeast single and double deletion mutants of Doa4 and other proteins in the multivesicular-body (MVB) pathway in order to determine the role of Doa4 and other MVB proteins ... -
The effects of erythropoietin on transferrin receptor concentration in rat duodenum tissue
(2008)Preliminary studies showed factors contained in human milk retain their mitogenic activity following pasteurization. Iron is critical in cell proliferation in early life. Erythropoietin (Epo), a factor found in human milk, ... -
Effects of Manganese on (p)ppGpp Homeostasis in Bacillus subtilis
(2018-06-12)The bacterial nucleotide signal (p )ppGpp is an important signal for stress survival, antibiotic tolerance, and virulence in common pathogens. In addition, the group 7 metal manganese has been implicated in having critical ... -
Effects of Withaferin A on Mouse Models of Alexander Disease
(2015-05-06)Alexander disease is a rare neurodegenerative disorder which is caused by the accumulation of glial fibrillary acidic protein (GF AP) resulting in aggregates termed Rosenthal Fibers (RFs) in the central nervous system. TAR ... -
EGFR Signaling Promotes Invadosome-Mediated 3-D Axon Outgrowth
(2021)During development, axons and dendrites (collectively known as neurites) extend from neuron cell bodies to form appropriate synaptic connections, using secreted and cellsurface ligands as guides (Lowery & Vactor, 2009). ... -
Engineering of maltose-binding protein to employ a poly-arginine tag and improve protein purification
(2007)Maltose binding protein (MBP), a solubility-enhancing fusion protein, has demonstrated great success in the application of protein purification when fused to a protein of interest. It has already been engineered to include ... -
Essential Amino Acids have Additive Effects on TORC1 in Bovine Mammary Epithelial Cells (MAC-T)
(2021)Milk proteins are produced in mammary epithelial cells from amino acids (AA). Excess AA that are not used for protein synthesis are excreted by the cow as nitrogenous (N) waste products through urine. Excretion of N waste ... -
Evaluating Nonstructural Carbohydrates in Cranberry (Vaccinium macrocarpon Ait.) Cultivars and their Role in Fruiting
(2014)Carbohydrate competition within cranberry (Vaccinium macrocarpon Ait.) uprights has been suggested to explain biennial bearing. Although, comparisons across cultivars during critical phenological stages are limited. The ... -
Exploration of the relationship between GRAIL and Cbl-b
(2010)The E3 ligases GRAIL and Cbl-b are necessary for the induction of CD4+ T cell anergy. Using CD4+ T cells from wildtype (WT) and Cbl-b knockout (Cbl-B -/-) mice, we investigated the relationship between GRAIL and Cbl-b. ... -
Exploring the role of Na+\H+ exchanger in neonatal brain injuring following hypoxia-ischemia
(2010)We investigated the role of Na+/H+ exchanger isoform 1 (NHE-1) in neonatal hypoxia ischemia (HI). HI was induced by unilateral ligation of the left common carotid artery is postnatal day 9 (PN) mice, and subsequent exposure ... -
Fine mapping for domestication traits using recombinant chromosome nearly isogenic lines
(2017-06-13)In past work the Doebley Lab used maize-teosinte hybrid recombinant inbred lines (RILs) to find various quantitative trait loci (QTL) for ear size in order to study the process of domestication. Of particular interest was ... -
Functional changes in gut microbiota across the hibernation cycle of Ictidomys tridecemlineatus examined by stable isotope-assisted labeling
(2018-06-12)The hibernation cycle of the 13-lined ground squirrel, which includes fasting during winter months, drives changes in taxonomic composition of the gut microbiota. This study employs stable isotope-assisted labeling (SlAL) ... -
Functional differences between the yeast Hsp70 molecular chaperones Ssbl and Ssb2
(2011)Protein folding is a complex process that is mediated in the cell by molecular chaperones. Errors in protein folding can lead to aggregation of rnisfolded proteins, causing diseases such as Alzheimer's disease and ... -
A genetic approach to understanding co-regulated MAPK genes in Arabidopsis thaliana
(2007)Mitogen-activated protein kinase (MAPK) signaling cascades connect cellular signal and gene transcription in cells. The pathway can regulate cell division, cell growth, and other pathways in eukaryotes. We used the ... -
Genetic studies of the velC gene required for proper sexual development in Aspergillus nidulans
(2010)VelC is required for the proper fungal development in Aspergillus nidulans. Velvet proteins, VeA, VosA, VelB, and VelC, are a new protein family in many filamentous fungi. They regulate fungal development and secondary ... -
Herbivory defense in Mimulus quttatus (yellow monkeyflower): consequences for generalist and specialist herbivores
(2012)Plants have undergone strong selection from herbivory, resulting in diverse physical and chemical defenses. Chemical defenses deter generalist herbivores, but are often tolerated by specialists. Mimulus guttatus (yellow ... -
Identification of the Functional Domains of Arabidopsis FLS2
(2007)Arabidopsis FLS2 is a leucine-rich repeat (LRR) transmernbrane receptor-kinase that recognizes bacterial flagellin and induces plant innate immune responses. Flg22 is a 22 amino acid peptide based on a sequence of flagellin ... -
Identification of two binding partners for the bacterial actin homolog MreB
(2007)A distinguishing characteristic of prokaryotes was long thought to be the lack of a cytoskeleton similar to eukaryotes consisting of actin filaments, microtubules, and intermediate filaments. However, recent work has shown ...