Browsing College of Agricultural and Life Sciences Honors and Undergraduate Research Program by Subject "Genetics"
Now showing items 6-25 of 30
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The effects of the Anopheles gambiae CLIPC3 and CLIPC1 genes on melanization of an abiotic target
(2007)Melanization is a mechanism of innate immunity in arthropods wherein a thick capsule of melanin is formed around foreign objects. Little is known about this pathway biochemically though serine proteases are known to ... -
Evaluating the effects of a possible therapeutic drug for Rett Syndrome in a mouse model
(2010)Rett Syndrome (RTT) is a neurodevelopmental disorder that affects girls with an estimated prevalence of 1 in 10,000-15,000, with no current cure or effective treatment. Most RTT cases are caused by human methyl-CpG binding ... -
Examining cell shape as the mechanism for furrow positioning in the early Zebrafish (Danio rerio) embryo
(2010)Through previous studies, it has been found that Zebrafish embryos show a predictable pattern of cell division consisting of the spindle apparatus always aligning perpendicular to its orientation in the previous cell stage. ... -
Exploring Senataxin -- Sen1p homology
(2010)Mutated SETX, a human gene encoding for the protein Senataxin, has been identified among patients with two different neurodegenerative disorders--ataxia-ocular apraxia 2 (AOA2) and amyotrophic lateral sclerosis 4 (ALS4). ... -
Female California mouse scent marking behavior and its implications for the pair bond
(2013)Scent marking has been shown to be an active form of communication for male mice in claiming territory, advertising for females, and mate guarding. Yet little is known about how females use scent marking behaviorally. ... -
A genetic approach to understanding co-regulated MAPK genes in Arabidopsis thaliana
(2007)Mitogen-activated protein kinase (MAPK) signaling cascades connect cellular signal and gene transcription in cells. The pathway can regulate cell division, cell growth, and other pathways in eukaryotes. We used the ... -
Going from embryo to adult: How zebrafish zic genes are regulated during development
(2009)This project aims to further our understanding of developmental genetics by identifying unknown transcription factor binding sites that play an important role in regulating zic2a, a gene required for proper neural development ... -
Haplotype frequencies at the miR156 and miR172 transcript regions show a significant response to divergent recurrent selection for vegetative phase change in maize
(2009)Sweet corn (Zea mays L). plants that transition from juvenility to the adult phase earlier during development are generally more resistant to common rust (Puccinia sorghi), a disease that causes substantial yield loss in ... -
The Identification and Characterization of Cytoplasmic Acetylated Lysines
(2011)Lysine acetylation by histone acetyl transferascs (HATs) is a reversible posttranscriptional modification that plays a key role in regulating several biological processes, such as the cell cycle, nuclear transport, and ... -
Identification Of Acetylated Lysine Residues On The ER Chaperone BiP
(2011)Alzheimer's disease (AD) pathogenesis involves the abnormal production of a small peptide called Abeta. The rate-limiting enzyme for the generation of Abeta is BACEl and, as such, its downregulation decreases Abeta levels. ... -
Identification of QTLs for voluntary running activity in mice for the CBA/J and DBA/2J mouse strains
(2009)Our goal is to understand the genetic factors related to voluntary running activity. Voluntary running activity in humans and mice is known to be a heritable behavioral trait. The genetic factors influencing voluntary ... -
An investigation on the effects of mutations in the ATG12 autophagy pathway of Arabidopsis thaliana
(2007)Under nutrient-deficient conditions, plants are forced to recycle secondary cellular constituents to conserve energy for the more essential processes (Klionsky, et al. 2000). Plants accomplish this through a process called ... -
Pilot screen for second site suppressors of wstd
(2009)Triosephosphate isomerase (TPI) loss of function (wstd), in flies has been shown to have increases in methylglyoxal and advanced glycation end products (AGEs) which have also been found in increased levels in diseases ... -
Preneoplastic Lesion Growth in B6.Hcs7C3H 219R8 Congenic Hepatocarcinogen-Sensitive Mus musculus
(2009)A region of mouse Chromosome 1, called the Hcs7 locus, is involved in the susceptibility to liver carcinogenesis in the inbred mouse strain, C3H/HeJ (C3H). Linkage analysis of a cross between C3H and a strain that is ... -
Reduction of androgen induced reactive oxygen species (ROS) production as a method of preventing prostate cancer
(2007)Prostate cancer is a leading cause of cancer deaths among men and development of a preventative agent is urgently needed. Reactive oxygen species (ROS) are carcinogens and are linked to prostate tumor development. ROS ... -
A role for FoxQ-1 in memory and learning
(2010)Using a genome-wide screen, genes that were differentially expressed between aged rats that were able to learn a spatial task (aged superior learners: SL), and learning-impaired rates (AI) were identified in the CA1 region ... -
The role of a soluble, competitive FGF receptor in embryonic stem cell-derived hematopoiesis
(2007)The fibroblast growth factor (FGF) signaling pathway plays a pivotal role in the maintenance of embryonic stem cells (ESCs) as well as their differentiation into the hematopoietic lineage. We observed that supplementing ... -
The role of dynamin and Rho1 during cytokinesis in C. elegans
(2008)Cytokinesis is the final phase of cell division in which a single cell is physically separated into two daughter cells. This is accomplished by constricting the acto-myosin contractile ring and inserting new membrane along ... -
Semantic category learning through explicit and implicit knowledge of complex sequences
(2009)Objects with similar functions are judged to be similar "kinds of things," even when they have few directly-observable properties in common. How do people learn such "functional" similarity? One possibility is that objects ... -
Starvation responses of invasive and non-invasive Eurytemora affinis populations
(2007)Within the past century, the copepod Eurytemora affinis have invaded freshwater from saline sources throughout the Northern Hemisphere. Two genetically divergent clades (Atlantic and North Atlantic) of E. affinis coexist ...