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RNAinterference Identifies Genes Important for Cilia Structure and Function
File(s):
- BraunreiterSpr2012.pdf (2.703Mb PDF)
- Author(s)
- Advisor(s)
- Lyman Gingerich, Jamie S.
- Date
- Apr 2012
- Subject(s)
- RNA; Genes--Identification; Cilia and ciliary motion; Posters
- Series
- USGZE AS589
- Abstract
- Primary cilia are cellular antennae that mediate responses to the external environment. Response requires perception of a cue and transmission of that signal to the cell. This study employed a reverse genetic strategy known as RNAinterference to systematically reduce the function of each gene chromosome I and examine the effects on PKD-2 localization in C. elegans. Once the genes have been identified that affect PKD-2 localization, the role of these genes in cilia structure and function will be examined.
- Description
- Color poster with text, images, and charts.
- Sponsor(s)
- University of Wisconsin--Eau Claire Office of Research and Sponsored Programs; National Institutes of Health grant; Kell Container award.
- Permanent link
- http://digital.library.wisc.edu/1793/61839
- Export
- Export to RefWorks