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RNAinterference Identifies Genes Important for Cilia Structure and Function

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Author(s)
Braunreiter, Kara; Gabrhel, Casey
Advisor(s)
Lyman Gingerich, Jamie S.
Date
Apr 2012
Subject(s)
RNA; Genes--Identification; Cilia and ciliary motion; Posters
Series
USGZE AS589
Abstract
Primary cilia are cellular antennae that mediate responses to the external environment. Response requires perception of a cue and transmission of that signal to the cell. This study employed a reverse genetic strategy known as RNAinterference to systematically reduce the function of each gene chromosome I and examine the effects on PKD-2 localization in C. elegans. Once the genes have been identified that affect PKD-2 localization, the role of these genes in cilia structure and function will be examined.
Description
Color poster with text, images, and charts.
Sponsor(s)
University of Wisconsin--Eau Claire Office of Research and Sponsored Programs; National Institutes of Health grant; Kell Container award.
Permanent link
http://digital.library.wisc.edu/1793/61839 
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