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Feasibility study: Comparison of performance status with objective physical activity monitors in lung cancer patients

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dc.contributor.advisor Campbell, Tony (Mentor)
dc.contributor.author Damodaran, Swathi
dc.date.accessioned 2010-07-21T17:41:08Z
dc.date.available 2010-07-21T17:41:08Z
dc.date.issued 2010
dc.identifier.uri http://digital.library.wisc.edu/1793/46046
dc.description 17 p. en
dc.description.abstract Context: Performance status (PS) is a predictor of response to chemotherapy but difficult to identify in patients with advanced lung cancer. It is measured using the ECOG scale, which relies on simple questions to assign a score. Accuracy in measurement is a concern. PS is closely related to physical activity, but they are not the same. Objective: To determine the feasibility of using two activity monitoring devices to examine physical activity and relate it to the PS assessment of lung cancer patients. Methods: Patients weare activPAL(TM) and Actigraph(TM) monitors for two weeks around a dose of chemotherapy. Results: Two patients have been evaluated of a planned 25. Initial results are: Subject 1: Actigraph(TM) Activity: 46,088 plus-or-minus 4286; activPAL(TM) Energy: 18.7 plus-or-minus 1.8; ECOG PS at Week 1: 1. Subject 2: Actigraph(TM) Activity: 176,591 plus-or-minus 5405; activPAL(TM) Energy: 20.1 plus-or-minus 0.3; ECOG PS at Week 1: 1. Conclusions: Actigraph(TM) shows a difference in activity between the two patients, but activPAL(TM) does not. Despite the difference in activity, both patients received an ECOG PS of 1. We hope to compare the devices and assess their correlation to PS assessment. Predictive and prognostic factors based on physical activity may then be further explored. en
dc.description.provenance Submitted by Beverly Phillips (bphillips@library.wisc.edu) on 2010-07-21T14:31:30Z No. of bitstreams: 1 2010_Damodaran.pdf: 1168128 bytes, checksum: 832fe3d754a30e2b98b2d0e49ac321bc (MD5) en
dc.description.provenance Approved for entry into archive by Beverly Phillips(bphillips@library.wisc.edu) on 2010-07-21T17:41:08Z (GMT) No. of bitstreams: 1 2010_Damodaran.pdf: 1168128 bytes, checksum: 832fe3d754a30e2b98b2d0e49ac321bc (MD5) en
dc.description.provenance Made available in DSpace on 2010-07-21T17:41:08Z (GMT). No. of bitstreams: 1 2010_Damodaran.pdf: 1168128 bytes, checksum: 832fe3d754a30e2b98b2d0e49ac321bc (MD5) Previous issue date: 2010 en
dc.language.iso en_US en
dc.rights The author grants to the University of Wisconsin-Madison the permission to reproduce and to distribute publicly paper and electronic copies of this thesis document in whole or in part in any medium now known or hereafter created. en
dc.subject Neurobiology en
dc.subject Medicine en
dc.subject Biology en
dc.title Feasibility study: Comparison of performance status with objective physical activity monitors in lung cancer patients en
dc.type Thesis en
thesis.degree.level BS en

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