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Author(s)

Yang, Chee; Greene, Alexander J.; Rauschnot, James C.

Advisor(s)

Hati, Sanchita; Bhattacharyay, Sudeep

Date

Apr 2009

Subject(s)

Oxidoreductases; Quinone reductases; Flavins; Posters

Series

USGZE AS589

Abstract

NRH:quinone oxidoreductase is a flavoenzyme that catalyzes the one-step reduction of quinones to hydroquinones using its cofactor, FAD. The enzyme kinetics goes through a "ping-pong" mechanism, in which changes in the flavin redox state control substrate binding and release. In this study, we are studying the slower dynamics of the subunit interface (surrounding the active site) using Normal Mode Analysis and exploring its relationship with the faster local motions.

Description

Color poster with text, charts, and diagrams.

Sponsor(s)

University of Wisconsin--Eau Claire Office of Research and Sponsored Programs.

Permanent link

http://digital.library.wisc.edu/1793/36941 

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Part of

• Student Research Day
  Posters of collaborative student/faculty research presented at Student Research Day

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