| dc.contributor.advisor |
Eide, David |
|
| dc.contributor.author |
Mateo, Michael |
|
| dc.date.accessioned |
2007-09-12T14:55:49Z |
|
| dc.date.available |
2007-09-12T14:55:49Z |
|
| dc.date.issued |
2007 |
|
| dc.identifier.uri |
http://digital.library.wisc.edu/1793/18285 |
|
| dc.description |
17 p. |
en |
| dc.description.abstract |
Pathogenic fungi have a major impact on human health. There is a lack of good therapies and some pathogenic fungi are resistant to the existing treatments. One possible target for treatment is covalently bonded cell wall protein 12 (CCW12), which is a cell wall protein that is needed for structural stability of the fungal cell wall. CCW12 is also induced in low zinc conditions by Zap1, which is a protein that is involved in transcriptional regulation in response to zinc. The goal of this study was to determine why CCW12 is up-regulated in low zinc conditions by Zap1. A number of experiments were conducted and seem to indicate that the CCW12 is up-regulated in low zinc to help stabilize the cell wall. More studies should be done to clarify the role of CCW12 and to investigate possible treatment for fungal infections. |
en |
| dc.description.provenance |
Submitted by Beverly Phillips (bphillips@library.wisc.edu) on 2007-09-12T14:54:37Z
No. of bitstreams: 1
michael_mateo_2007.pdf: 174416 bytes, checksum: 2e91c05cc46cc1ab3df58f5ec7b35bbb (MD5) |
en |
| dc.description.provenance |
Approved for entry into archive by Beverly Phillips(bphillips@library.wisc.edu) on 2007-09-12T14:55:49Z (GMT) No. of bitstreams: 1
michael_mateo_2007.pdf: 174416 bytes, checksum: 2e91c05cc46cc1ab3df58f5ec7b35bbb (MD5) |
en |
| dc.description.provenance |
Made available in DSpace on 2007-09-12T14:55:49Z (GMT). No. of bitstreams: 1
michael_mateo_2007.pdf: 174416 bytes, checksum: 2e91c05cc46cc1ab3df58f5ec7b35bbb (MD5) |
en |
| dc.format.extent |
174416 bytes |
|
| dc.format.mimetype |
application/pdf |
|
| dc.language.iso |
en_US |
en |
| dc.subject |
Nutritional Sciences |
en |
| dc.title |
Importance of CCW12 gene expression in zinc deficient Saccharomyces cerevisiae |
en |
| dc.type |
Thesis |
en |
