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Nutritional Sciences Honors Theses and Research Papers >
Please use this identifier to cite or link to this item:
http://digital.library.wisc.edu/1793/18285
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| Title: | Importance of CCW12 gene expression in zinc deficient Saccharomyces cerevisiae |
| Authors: | Mateo, Michael |
| Advisors: | Eide, David (Mentor) |
| Keywords: | Nutritional Sciences |
| Issue Date: | 2007 |
| Abstract: | Pathogenic fungi have a major impact on human health. There is a lack of good therapies and some pathogenic fungi are resistant to the existing treatments. One possible target for treatment is covalently bonded cell wall protein 12 (CCW12), which is a cell wall protein that is needed for structural stability of the fungal cell wall. CCW12 is also induced in low zinc conditions by Zap1, which is a protein that is involved in transcriptional regulation in response to zinc. The goal of this study was to determine why CCW12 is up-regulated in low zinc conditions by Zap1. A number of experiments were conducted and seem to indicate that the CCW12 is up-regulated in low zinc to help stabilize the cell wall. More studies should be done to clarify the role of CCW12 and to investigate possible treatment for fungal infections. |
| Description: | 17 p. |
| URI: | http://digital.library.wisc.edu/1793/18285 |
| Appears in Collections: | Nutritional Sciences Honors Theses and Research Papers
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Files in This Item:
| File |
Description |
Size | Format | Handle |
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| michael_mateo_2007.pdf | | 170Kb | Adobe PDF | http://digital.library.wisc.edu/1793/18286 | View/Open |
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